Cost of Single IRB Review
Paying for sIRB Review
The costs for IRB review at a single institution by that institution’s IRB have typically been considered an indirect cost covered under an institution’s Facilities and Administration (F&A) rate (except for industry-initiated-and-sponsored studies).
However, NIH expects that many sIRBs will charge fees to review other sites. The fees are the responsibility of the lead site and should be included in the grant budget. This is a new responsibility.
Which IRBs charge fees for serving as a single IRB?
Each IRB determines whether or not it will charge study-specific fees. In general:
- A NIH-operated IRB will not charge fees
- An “independent” IRB (e.g., WIRB, Advarra) will charge fees
- An IRB affiliated with a university, academic medical center or research institute may or may not charge fees.
See the list of options for single IRB review for UW PIs for more information about which specific IRBs charge fees.
Obtaining fee information for sIRB review
There is no nationwide standard for how IRB fees are assessed or how much they are. Some IRBs charge for each review action they complete (e.g. initial approval, modifications, continuing review) for each site. Some IRBs charge annual fees for the study based on the number of sites. For others, the fees vary based on institutional or organizational affiliations.
You should obtain fee information from the IRB that is specific to the study you are proposing. This may require asking the IRB office for a study-specific fee estimate. See the list of options for single IRB review for UW PIs for how to contact IRBs to obtain information about fees.
Grant budget guidance
- Which budget category on the SF424 (R&R) form should be used
- Which costs should be charged as direct vs. indirect costs under different IRB review scenarios
- The relationship with the $500,000 cap on direct costs
- Where to put the sIRB cost information on the budget forms
If you have questions, contact:
- The NIH financial officer identified in your FOA or RFP and/or
- Your department’s contact person at the UW Office of Sponsored Programs (OSP)