UW Research

Cystic Fibrosis Research Translation Center



The University of Washington Cystic Fibrosis Research Translation Center (CFRTC) focuses its research on developing new and improved treatments for patients with cystic fibrosis and understanding the impact of these new therapies on patient health. The Center has a long history of strong partnerships between laboratory and clinically based scientists working together to take observations from the laboratory and transforming these findings into better therapies to treat the nutritional, digestive, metabolic and lung aspects of CF. The CFRTC has 3 biomedical cores (Genomic, Host-Microbe, and Clinical), a pilot and feasibility program, and enrichment programs to encourage research collaborations.

The Specific Aims of the Center are to:

  • Enhance the research cores and other infrastructure for CF research in NIDDK interest areas that promotes creative, interdisciplinary and clinically-impactful CF research.
  • Provide expertise to researchers world-wide to design innovative clinical studies that determine best practice and develop new therapeutic approaches to correct dysfunctional CFTR and its secondary consequences.
  • Direct a pilot and feasibility grant program that attracts young and “new to CF” investigators, emphasizing support for investigators studying CF-related diabetes, GI disease, renal physiology, and other extra-pulmonary disease manifestations.
  • Train and mentor the next generation of laboratory, clinical, and biostatistical science leaders in CF locally and nationally.

Core Services Offered

Clinical Core: http://depts.washington.edu/cfrtc/clinical/
Host Microbe Core: http://depts.washington.edu/cfrtc/host-microbe/
Genomics Core: http://depts.washington.edu/cfrtc/genomics/
Pilot and Feasibility Program: http://depts.washington.edu/cfrtc/pilots/

Funding Information

NIH P30 DK089507: 7/6/2010-5/31/2025

Reporting Structure

David Sherman, PhD (Microbiology), Robb W. Glenny, MD, MA (Pulmonary Medicine) and Leslie Walker-Harding, MD (Pediatrics)

Related UW Entities

School of Medicine: Departments of Microbiology, Pediatrics, Laboratory Medicine, Genome Sciences, Comparative Medicine, Medicine (Divisions of Pulmonary and Critical Care Medicine and Metabolism, Endocrinology and Nutrition)

School of Public Health: Departments of Health Systems and Population Health, Global Health

School of Pharmacy: Department of Pharmaceutics

External Partners

  • Seattle Children’s Research Institute
  • Fred Hutch