Department of Comparative Medicine

Jessica M. Snyder

Assistant Professor

D.V.M., Virginia Maryland Regional College of Veterinary Medicine, 2001
M.S., University of Washington, 2014
Diplomate, ACVIM (Neurology), 2005
Diplomate, ACVP (Anatomic), 2015

1-446 Box 357340, Seattle, WA 98195
E: snyderjm@uw.edu

About Dr. Snyder

Dr. Snyder’s research broadly involves the assessment of pre-clinical animal models developed to address unmet translational needs of human diseases. As a comparative pathologist, her focus is the examination and validation of animal model phenotypes and evaluation of treatments and interventions via the application of clinicopathologic and histopathologic diagnostic criteria and scoring systems. Her specific interests include rodent models of aging and large and small animal models of neuromuscular and central nervous system disease. She also assists investigators with aspects of study design and data interpretation. Dr. Snyder is the co-director of the Comparative Pathology Program. She co-coordinates CMED 514 and 512 and is an instructor in pathology rounds and rotations offered by the Department of Comparative Medicine (CMED 590; JPC sessions).

Selected Publications

The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance. Zhong G, Hogarth C, Snyder JM, Palau L, Topping T, Huang W, Czuba LC, LaFrance J, Ghiaur G, Isoherranen N. J Biol Chem. 2019 Jul 19;294(29):11166-11179. doi: 10.1074/jbc.RA119.009023. Epub 2019 Jun 5.

Validation studies for germ-free Smad3-/-mice as a bio-assay to test the causative role of fecal microbiomes in IBD. Paik J, Meeker S, Hsu CC, Seamons A, Pershutkina O, Snyder JM, Brabb T, Maggio-Price L. Gut Microbes. 2019 May 29:1-11. doi: 10.1080/19490976.2019.1611151. [Epub ahead of print]

Ontogeny of white matter, toll-like receptor expression, and motor skills in the neonatal ferret. Snyder JM,* Wood TR,* Corry K, Moralejo DH, Parikh P, Juul SE. Int J Dev Neurosci. 2018 Nov;70:25-33. doi: 10.1016/j.ijdevneu.2018.05.006. Epub 2018 May 20. *denotes authors contributed equally to work

Systemic AAV8-mediated gene therapy drives whole-body correction of myotubular myopathy in dogs. Mack DL, Poulard K, Goddard M, Latournerie V, Snyder JM, Grange RW, Elverman MR, Denard J, Veron P, Buscara L, Le Bec C, Hogrel J, Doering J, Meng H, Yang L, Liu F, O’Callaghan M, Gopal N, Kelly VE, Smith BK, Strande JL, Mavilio F, Beggs AH, Mingozzi F, Lawlor MW, Buj-Bello A, and Childers MK. Mol Ther 25(4):839-854. doi: 10.1016/j.ymthe.2017.02.004, 2017.

Cause-of-Death Analysis in Rodent Aging Studies. Snyder JM, Ward JM, Treuting PM.  Vet Pathol. 53(2):233-43. doi: 10.1177/0300985815610391, 2016.

Correlation of Versican Expression, Accumulation, and Degradation during Embryonic Development by Quantitative Immunohistochemistry. Snyder JM, Washington IM, Birkland T, Chang MY, and Frevert CW.    J Histochem Cytochem 63(12):952-67. doi: 10.1369/0022155415610383, 2015.