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Research

A team of scientists at the University of Washington and the biotechnology company Illumina have created an innovative tool to directly detect the delicate, single-molecule interactions between DNA and enzymatic proteins. Their approach provides a new platform to view and record these nanoscale interactions in real time. As they report Sept. 28 in Nature Biotechnology, this tool should provide fast and reliable characterization of the different mechanisms cellular proteins use to bind to DNA strands — information that could shed new light on the atomic-scale interactions within our cells and help design new drug therapies against pathogens by targeting enzymes that interact with DNA.

The Fermi National Accelerator Laboratory — or Fermilab — announced that a 680-ton superconducting magnet is secure in its new home and nearly ready for a new era of discovery in particle physics. This achievement follows the delicate, 3,200-mile transport of the magnet’s 17-ton, 50-foot-wide housing ring to the U.S. Department of Energy facility outside Chicago two years ago. The fully assembled magnet will drive high-energy particle experiments as part of an international partnership among 34 institutions, of which the University of Washington is a leading contributor.

Leaders from the University of Washington and Shanghai Jiao Tong University (SJTU), one of China’s most prestigious public research universities, signed an agreement Wednesday to work together on “smart cities” research, teaching and collaborations in their respective electrical engineering departments.

Imagine a question-and-answer game played by two people who are not in the same place and not talking to each other. Round after round, one player asks a series of questions and accurately guesses the object the other is thinking about. Sci-fi? Mind-reading superpowers? Not quite. University of Washington researchers recently used a direct brain-to-brain connection to enable pairs of participants to play a question-and-answer game by transmitting signals from one brain to the other over the Internet. The experiment,…

For more than half a century, scientists have studied how the surface of the body is mapped in parts of the brain associated with touch. That research has focused largely on “body maps” that show how certain parts of the brain correspond point-for-point with the body’s topography. These body maps have been studied extensively in adult humans and other primates, but how they develop in babies, and how they relate to other aspects of infant development, have been little understood….

In early August, biologist Peter Ward returned from the South Pacific with news that he encountered an old friend, one he hadn’t seen in over three decades. The University of Washington professor had seen what he considers one of the world’s rarest animals, a remote encounter that may become even more infrequent if illegal fishing practices continue. The creature in question is Allonautilus scrobiculatus, a species of nautilus that Ward and a colleague had previously discovered off of Ndrova Island…

Women lag behind men in the lucrative computer science and technology industries, and one of the possible contributors to this disparity is that they’re less likely to enroll in introductory computer science courses. A new study of 270 high school students shows that three times as many girls were interested in enrolling in a computer science class if the classroom was redesigned to be less “geeky” and more inviting. The results, by University of Washington researchers, reveal a practical way…

The public sector has long served as an equalizer in American society, a place where minority workers could find stable employment that offered advancement and a reliable path to a middle-class life. But the Great Recession wiped out many of those jobs, as tax revenues declined and anti-government sentiment added to a contraction that continued long after the recession ended in 2008. Those job cuts disproportionately hurt African-American workers and increased racial disparity in the public sector, a new study…

Ever been so hungry that you can’t think of anything but finding food? Research from the UW Foster School of Business finds that the single-mindedness that results from hunger makes people more likely to commit unethical acts to satisfy that hunger — but less likely to lie, cheat or steal for reasons that don’t address the immediate physiological need.

Children who have been abused or exposed to other types of trauma typically experience more intense emotions than their peers, a byproduct of living in volatile, dangerous environments. But what if those kids could regulate their emotions? Could that better help them cope with difficult situations? Would it impact how effective therapy might be for them? A University of Washington-led team of researchers sought to address those questions by studying what happens in the brains of maltreated adolescents when they…

Recent press and social media coverage have reminded residents of the Pacific Northwest that they live in a seismically active region. Stretching offshore from northern California to British Columbia, the Cascadia subduction zone could slip at any time, causing a powerful earthquake and triggering a tsunami that would impact communities along the coast. Scientists from multiple disciplines at the University of Washington and other institutions are learning more about this hazard. Dozens of UW scientists are part of the M9…

A team of scientists has identified a new species of “pre-mammal” based on fossils unearthed in Zambia’s Luangwa Basin in 2009. The ancient, Dachshund-sized creature lived some 255 million years ago, in a time just before the largest mass extinction in Earth’s history. Its discoverers include Christian Sidor, professor of biology at the University of Washington and curator of vertebrate paleontology at the Burke Museum of Natural History and Culture. Sidor and his colleagues, who announced their finding in July…

The signs that an abused child might later commit crimes might not be obvious — that boisterous playground behavior from a third-grade boy, for example, or the 10-year-old girl who seems a little anxious or withdrawn. But new research from the University of Washington suggests that troubling behaviors exhibited by abused children can be predictors of later criminal activity, and that those indicators differ between boys and girls. The study, published Aug. 11 in the Journal of Interpersonal Violence, found…

Abusive and controlling men are more likely to put their female partners at sexual risk, and the level of that risk escalates along with the abusive behavior, a UW study found. Published in the Journal of Sex Research in July, the study looked at patterns of risky sexual behavior among heterosexual men aged 18 to 25, including some who self-reported using abusive and/or controlling behaviors in their relationships and others who didn’t. The research found that men who were physically…

Crystals play an important role in the formation of substances from skeletons and shells to soils and semiconductor materials. But many aspects of their formation are shrouded in mystery. Scientists have long worked to understand how crystals grow into complex shapes. Now, an international group of researchers has shown how nature uses a variety of pathways to grow crystals beyond the classical, one-piece-at-a-time route. “Because crystallization is a ubiquitous phenomenon across a wide range of scientific disciplines, a shift in…

The UW is investing up to $37 million in the Washington Nanofabrication Facility, which makes things for researchers and outside companies that aren’t practical, economical or possible to fabricate at commercial foundries: inconceivably tiny devices, chips made from unconventional materials that industrial factories won’t touch and devices that probe the boundaries of our universe.