Drug treatments can save lives, but sometimes they also carry unintended costs. After all, the same therapeutics that target pathogens and tumors can also harm healthy cells. To reduce this collateral damage, scientists have long sought specificity in drug delivery systems: A package that can encase a therapeutic and will not disgorge its toxic cargo until it reaches the site of treatment — be it a tumor, a diseased organ or a site of infection. In a paper published Jan….
Scientists at the University of Washington show for the first time that the complex distribution of molecules within a membrane of a living yeast cell arises through demixing.
Kim Nasmyth, a professor of biochemistry at the University of Oxford and former postdoctoral researcher at the University of Washington, is one of five recipients of the 2018 Breakthrough Prize in Life Sciences. Nasmyth and other prize recipients were honored by the Breakthrough Prize Foundation at a ceremony December 3 at NASA’s Ames Research Center in Mountain View, California.
Three University of Washington faculty members are among those honored with an NIH High-Risk, High-Reward Research grant, which fund exceptionally creative scientists proposing to use highly innovative approaches to tackle major challenges in biomedical research.
University of Washington researchers are developing a smartphone app that is capable of objectively detecting concussion and other traumatic brain injuries in the field, which could provide a new level of screening for athletes and accident victims.
A new app could lead to earlier detection of pancreatic cancer simply by snapping a smartphone selfie. The disease kills 90 percent of patients within five years, in part because there are no telltale symptoms or non-invasive screening tools to catch a tumor before it spreads.
Scientists at the University of Washington have discovered a simple way to raise the accuracy of diagnostic tests for medicine and common assays for laboratory research. By adding polydopamine — a material that was first isolated from shellfish — to these tests at a key step, the team could increase the sensitivity of these common bioassays by as many as 100 to 1,000 times.
A new UW microscope could provide real-time results during cancer-removal surgeries, potentially eliminating the 20 to 40 percent of women who have to undergo multiple lumpectomy surgeries because cancerous breast tissue is missed the first time around.
Neighborhoods with greater poverty and disorganization may play a greater role in problem drinking than the availability of bars and stores that sell hard liquor, a University of Washington-led study has found. While there is evidence for the link between neighborhood poverty and alcohol use, the new twist — that socioeconomics are more powerful environmental factors than even access to the substance itself — suggests that improving a neighborhood’s quality of life can yield a range of benefits….
As the World Health Organization steps up its efforts to eradicate a once-rampant tropical disease, a University of Washington study suggests that monitoring, and potentially treating, the monkeys that co-exist with humans in affected parts of the world may be part of the global strategy. Yaws, an infectious disease that causes disfiguring skin lesions and bone destruction — stems from a bacterium, Treponema pallidum, that also has been found in certain primates in Africa and Asia. The disease, treatable…
The interdisciplinary 2017 Benjamin Rabinowitz Symposium in Medical Ethics on March 31, titled “Race, Health & Justice,” will explore inequities in health and health care and place them in political, economic and historical context.
Three faculty members at the University of Washington have been awarded early-career fellowships from the Alfred P. Sloan Foundation. The new Sloan Fellows, announced Feb. 21, include Ali Farhadi, assistant professor of computer science and engineering; Emily Levesque, assistant professor of astronomy; and John Tuthill, assistant professor of physiology and biophysics.
By using magnetic resonance imaging (MRI) to study the brains of infants who have older siblings with autism, scientists were able to correctly identify 80 percent of the babies who would be subsequently diagnosed with autism at 2 years of age.
In a paper published Jan. 17 in the journal Nature Communications, researchers report that fruit flies — perhaps the most widely studied insect in history — show signs of rational decision-making when choosing a mate.
Two University of Washington professors have received the 2017 Presidential Early Career Award for Scientists and Engineers, the highest honor given by the U.S. government to early career scientists and engineers.
For the first time in humans, UW Center for Sensorimotor Neural Engineering (CSNE) researchers have used direct stimulation of the human brain surface to provide basic sensory feedback through artificial electrical signals, enabling patients to control movement while opening and closing their hand.
Accelerating growth in effectively delivering new oral and transdermal drug delivery techniques will be the focus of the University of Washington Department of Bioengineering’s 2016 Allan S. Hoffman Lecture on Oct. 10.
Amid a decline in funding for scientific research, the Howard Hughes Medical Institute is partnering with the Bill & Melinda Gates Foundation and the Simons Foundation to launch a new Faculty Scholars program. Announced Sept. 22 by HHMI, the inaugural crop of early-career scientists includes 5 faculty members from the University of Washington.
Researchers at the University of Washington are among the winners of a startup challenge to shorten the transition time from lab bench to patient. The team, including members of professor Suzie Pun’s research group in the UW Department of Bioengineering, was selected based on its proposal and business plan to develop a targeted drug delivery system for breast cancer.
Scientists from the University of Washington recently reported a relatively simple method swell the tiny, complex structures within cells, bringing them within range of a common microscope’s resolving range.
In a White House ceremony May 19, President Barack Obama presented the National Medal of Science to Mary-Claire King, University of Washington professor of genome sciences and medicine. The award, the nation’s highest recognition for scientific achievement, honors King’s more than 40 years dedicated to research in evolution and the genetics of human disease, as well as to teaching and outreach endeavors that have supported human rights efforts on six continents and reunited families.
The University of Washington is home to 26 researchers included on Thomson Reuters’ list of “The World’s Most Influential Scientific Minds” for 2015, which was released Jan. 14. The distinction, based on an analysis of over a decade of research paper citations among 21 general scientific fields, is meant to recognize scientists who are most cited by their peers.
In December, the University of Washington’s Department of Bioengineering began accepting applications for its newest graduate degree program, the Master of Applied Bioengineering. The one-year, full-time program begins in August, and will train students to apply engineering design and entrepreneurship skills to address unmet clinical needs and to transform biomedical research into technologies for improving health care. The degree will position graduates to respond to market-based demands of industry, medicine and translational research.
Three scientists at the University of Washington have proposed a way to speed up common bioassays used in research and diagnostics. Their solution, reminiscent of the magic behind washing machines, could reduce wait times to a fraction of what they once were. As they report in the journal Small, biological assays that once took hours could instead take minutes.
Four University of Washington researchers are among 347 new fellows of the American Association for the Advancement of Science for 2015.
Two University of Washington faculty members have been awarded a grant from The Swartz Foundation to support research in theoretical neuroscience. The award establishes the UW as the latest of the Swartz Foundation-supported centers for innovation in this growing field, which spans mathematics, statistics, physics and biology. “This award is a recognition of what is happening here at the UW in theoretical neuroscience research,” said Adrienne Fairhall, a UW associate professor in the Department of Physiology and Biophysics. “It is…
A UW otolaryngology resident and bioengineering student have used 3-D printing techniques to create lifelike models to help aspiring surgeons – who currently practice on soap, apples, and vegetables – learn to perform ear reconstruction surgeries.
UW researchers have produced cell-to-cell communication in baker’s yeast — a first step in learning to build multicellular organisms or artificial organs from scratch.
The gold standard for diagnosing sleep apnea — a disease which affects roughly 1 in 13 Americans — requires an overnight hospital stay and costs thousands of dollars. A new smartphone app developed at the University of Washington can wirelessly test for sleep apnea events in a person’s own bedroom without needing special sensors attached to the body.
Researchers from the University of Washington have teamed up with medical device manufacturer Medtronic to use the Activa® PC+S Deep Brain Stimulation (DBS) system with people who have essential tremor.
University of Washington researchers have developed a new injectable polymer that strengthens blood clots, called PolySTAT. Administered in a simple shot, the polymer finds any unseen injuries and has the potential to keep trauma patients from bleeding to death before reaching medical care.
Mary-Clare King, a world leader in cancer genetics and the application of genetics to justice for human rights violations, will be honored by the Albert and Mary Lasker Foundation.
Latest news from the UW Health Sciences: Comparative genomes, open notes, teaching Ebola, depression in women
University of Washington bioengineers have discovered a potentially faster way to deliver a topical drug that protects women from contracting HIV. Their method spins the drug into silk-like fibers that quickly dissolve when in contact with moisture, releasing higher doses of the drug than possible with other materials.
University of Washington bioengineers have a designed a peptide structure that can stop the harmful changes of the body’s normal proteins into a state that’s linked to widespread diseases such as Alzheimer’s, Parkinson’s, heart disease, Type 2 diabetes and Lou Gehrig’s disease.
A low-cost technique may make DNA sequencing more convenient and less cumbersome, perhaps eventually replacing large lab machines with hand held devices.
Health Digest is a selection of recent news and features from the UW Health Sciences/UW Medicine.
Benjamin Hall and Eric D’Asaro are among the 84 new members elected fellows the National Academy of Sciences.
Health Digest is UW Today’s round-up of news stories from UW Health Sciences, compiled by News and Information.
The UW School of Medicine plans to establish Spokane as the center of an effort called “Next Generation WWAMI.”