The removal of a regulator gene that allows the tuberculosis bacterium to remain dormant in laboratory studies could point the way to new treatments for many tuberculosis patients. Research at the University of Washington by Dr. David Sherman, assistant professor of pathobiology in the School of Public Health and Community Medicine, and his colleagues shows that by interrupting the function of this gene, the tuberculosis bacterium is unable to mount the appropriate genetic response. It thus may be unable to become dormant.
June 18, 2001