The National Institutes of Health seeks applicants for $200 million in grants under the American Recovery and Reinvestment Act for large-scale research projects that are likely to spur growth and investment in biomedical research, public health and health care delivery. Funding priorities include research on information technology that lets physicians share radiological images across health care organizations to reduce health care costs and improve decision-making. Applications are due by May 27.
Category: Biomedical Research
President Obama Reverses Stem Cell Research Ban, Issues New Research Guidelines
Yesterday, President Obama lifted a ban on the use of federal funds for research on embryonic stem cell lines created after August 2001. The executive order directs the National Institutes of Health to develop appropriate guidelines for the research. President Obama’s decision reverses the order issued by President Bush on August 9, 2001, which limited federal research funding to embryonic stem cell lines already in existence on that date. The new order does not lift the congressional ban on the use of federal funds to create new embryonic stem cell lines, but it does allow scientists to use federal funding to study the hundreds of new cell lines that have been created since 2001. Continue reading “President Obama Reverses Stem Cell Research Ban, Issues New Research Guidelines”
NIH Releases Details on Additional Recovery Act Opportunities
On March 5th, the National Institutes of Health (NIH) made available on its website additional information and announcements about grant opportunities created by the American Recovery and Reinvestment Act of 2009 (ARRA). The announcements and background information are posted on the NIH ARRA website.
NIH Announces ARRA Challenge Grant RFA
Introducing the NIH Challenge Grant RFA OD-09-003
NIH has received new funds for Fiscal Years 2009 and 2010 as part of the American Recovery & Reinvestment Act (ARRA) of 2009 (Recovery Act). The NIH has designated at least $200 million in FYs 2009 – 2010 for a new initiative called the NIH Challenge Grants in Health and Science Research.
This new program will support research on topic areas that address specific scientific and health research challenges in biomedical and behavioral research that would benefit from significant 2-year jumpstart funds.
The NIH has identified a range of Challenge Areas that focus on specific knowledge gaps, scientific opportunities, new technologies, data generation, or research methods that would benefit from an influx of funds to quickly advance the area in significant ways. Each NIH Institute, Center, and Office has selected specific Challenge Topics within the broad Challenge Areas related to its mission. The research in these Challenge Areas should have a high impact in biomedical or behavioral science and/or public health.
NIH anticipates funding 200 or more grants, each of up to $1 million in total costs, pending the number and quality of applications and availability of funds. In addition, Recovery Act funds allocated to NIH specifically for comparative effectiveness research (CER) may be available to support additional grants. Projects receiving these funds will need to meet this definition of CER: “a rigorous evaluation of the impact of different options that are available for treating a given medical condition for a particular set of patients. Such a study may compare similar treatments, such as competing drugs, or it may analyze very different approaches, such as surgery and drug therapy.” Such research may include the development and use of clinical registries, clinical data networks, and other forms of electronic health data that can be used to generate or obtain outcomes data as they apply to CER.
NIH Outlines Spending Plan for $10.4 Billion of Economic Recovery Package Funding
Today in a briefing at the American Association for the Advancement of Science, Acting NIH Director Raynard Kington provided an outline of the plan his agency will utilize to spend the $10.4 billion provided in the American Recovery and Reinvestment Act of 2009. However, Dr. Kington mentioned many times during the briefing that the details of the plan are still being worked out within NIH and the Office of Management and Budget. NIH plans to obligate the funding provided within two years and does not assume that funding will be added to the base budget. He added that there will be no across-the-board percentage increases in grants or programs.
Dr. Kington emphasized that use of the economic recovery money would not be business as usual; there will be unprecedented reporting requirements, such as information on economic impact and the number of jobs created and retained as a result of a research grant.
Dr. Kington described the funding streams in the bill as follows:
- $8.2 billion for research activities, of which $7.4 billon is to be allocated across the NIH Institutes, Centers, Divisions, and the Common Fund (which includes cross-cutting activities such as the NIH Roadmap); $800 million will remain in the Office of the Director;
- $1 billion for extramural construction, repairs, and alterations through the National Center for Research Resources (NCRR); the review process for construction and renovation projects has not been determined (operating funds will not be provided);
- $300 million for shared instrumentation;
- $500 million for construction and improvements on the NIH campus; and
- $400 million transferred from the Agency for Healthcare Research and Quality for comparative effectiveness research.
Research funding will be allocated in three general ways:
- Funding of grant applications from FY08 and FY09 that were judged to be “highly scientifically meritorious” but not funded. Among the criteria of the selection process will be whether meaningful progress toward project goals can be achieved with two years of committed funds, rather than the usual four years of funding.
- Supplements to existing grants to accelerate and/or expand their work. This may include added equipment, training positions, and summer jobs for students. Such additions will not be made by formula, but will be based on scientific opportunity and public health needs. The new money will not be used to restore cuts made to project proposals during earlier negotiations.
- NIH Challenge Grants. There will be a “reasonable” number of awards made under this new program aimed at supporting cross-cutting research. The Institutes, Centers, and Divisions will have an opportunity to identify areas in which they would like to see applications. NIH will issue a Request for Applications for the program soon.
Funding will not be provided in a lump sum, but over a two year period. Given that we are dealing with funds intended to stimulate the nationally economy, geography will be a factor in awarding funding. Additionally, there will be some focus on new investigators and junior scientists. When asked if the grants would have carryover authority, Dr. Kington reminded participants that the money was intended as “a short-term stimulus” and said universities should not ask for money they didn’t think they could spend in two years. Dr. Kington explained that in rare cases, no-cost extensions may need to be granted. However, he also explained that at the end of two years, grants that have not been spent will draw scrutiny by government and result in significant embarassment to the scientific community. Dr. Kington did not give a timetable for the release of further details, but given the two-year timetable for use of funds, he expects details to be laid out in the next few weeks.