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Lucas Meza, an assistant professor of mechanical engineering at the University of Washington, started his lab to build a new generation of tough and light nanomaterials inspired by natural materials like wood, shell and bone. Instead, he discovered “big gaps” in our basic understanding of what makes a material tough or brittle. Meza spoke to UW News about his strange and surprising journey into the nano realm.

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint precise areas of the body can reduce the medicine dosage and avoid potentially harmful “off target” effects. Researchers at the UW took a significant step toward that goal by designing proteins with autonomous decision-making capabilities. By adding smart tail structures to therapeutic proteins, the team demonstrated that the proteins could be “programmed” to act based on the presence of specific environmental cues.

A new analysis of data from the Cassini space probe has identified organic compounds within jets of water ice erupting from Saturn’s moon Enceladus. Some of the compounds, which likely originated in Enceladus’ subsurface ocean, have never before been identified on another world beyond Earth. The study, conducted in part by a UW researcher, contributes to mounting evidence that Enceladus could support life.

The James Webb Space Telescope has revealed new details in the core of the Butterfly Nebula, known to astronomers as NGC 6302. From the dense ring of dust that surrounds the nebula’s core to the tiny but bright star hidden within, the Webb observations paint a never-before-seen portrait of the nebula’s inner workings. Researchers at the UW and around the world are studying the imagery to learn more about the origins of cosmic dust and its role in the formation of planets like ours.

Physicists have floated numerous theories to explain what dark matter might be, but to date, no experiment has turned up compelling evidence to support any of them. An international team of physicists, including researchers from the UW, is now working on a new kind of dark matter detector with the goal of capturing the first direct observation of the puzzling material. Results from the detector’s prototype have already ruled out one of the leading theories of how dark matter originated.

Antimicrobial resistance is a lurking threat in hospitals around the world. As more strains of bacteria and other microbes evolve defenses against available drugs, more patients run the risk of contracting infections that defy treatment. Now, University of Washington researchers offer new insights into measures currently used to control the spread of antibiotic resistant bacteria and other infectious agents in health care facilities.