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SCHOOL OF PUBLIC HEALTH
SCHOOL OF PUBLIC HEALTH
PUBLIC HEALTH GENETICS

Detailed course offerings (Time Schedule) are available for

To see the detailed Instructor Class Description, click on the underlined instructor name following the course description.

PHG 200 Implications of Public Health Genomics for the Modern World (3-5) I&S/NW Karen Edwards, Enquobahrie, Kuszler, McGrath
Introduces the field of public health genomics through examples of genetic, ethical, political, and social issues emerging in the wake of the Human Genome Project. Students develop the skills to analyze and critique public health, clinical, personal, and social implications resulting from emerging genomic technologies. Offered: A.
Instructor Course Description: Tara Bethanne Coffin

PHG 301 Introduction to Genetic Epidemiology (3) I&S/NW Edwards, Enquobahrie, Hutter
Explores basic approaches that are used to identify genetic and environmental factors in health and disease, and how application of this information can be used to improve population health. Discusses the relevant ethical, legal, and social implications that occur in research and translation to practice. Offered: W.
Instructor Course Description: Renee Agatsuma

PHG 302 Forensic Genetics (3) I&S/NW, QSR B. WEIR
Introduces the field of forensic genetics through discussion of genetic and statistical issues emerging since the introduction of DNA profiling. Students develop the skills to interpret the evidence of matching genetic profiles; to perform calculations relevant for parentage determination; the identification of remains; and to consider the implications of familial searching of DNA databases. Prerequisite: either BIOST 310, STAT 220, STAT 221/CS&SS 221/SOC 221, STAT 311, Q SCI 381, or Q METH 201. Offered: jointly with BIOST 302; Sp.

PHG 511 Genetic Epidemiology (3) Fullerton
Research methods for evaluating genetic influences on disease and risk factors and genetic-environmental interactions. Study designs and statistical methods include twin studies, family studies, population-based association studies, segregation analysis, and linkage analysis. Prerequisite: EPI 511, BIOST 511, and GENOME 371, or equivalent. Offered: jointly with EPI 517; Sp.

PHG 512 Legal, Ethical, and Social Issues in Public Health Genetics (3) Kuszler, Mastroianni
Equips the student to anticipate and assess potential legal, ethical, and social barriers complicating the incursion of new genetic advances, information, and technologies into public and private healthcare delivery efforts. Prerequisite: GENOME 361, GENOME 371, or equivalent. Offered: jointly with B H 514/LAW H 504; A.
Instructor Course Description: Anna C. Mastroianni

PHG 513 Basic Concepts in Pharmacogenetics and Toxicogenomics (3) Eaton, Thummel
Addresses current DNA sequencing and genotyping approaches, and basic concepts of pharmacogenetics and toxicogenomics. Emphasis placed on applications of genomic technologies to the understanding of "gene-environment interactions" that cause diseases of public health importance, including cancer, chronic neurological diseases, and adverse drug reactions. Offered: jointly with ENV H 513/PCEUT 513; W.
Instructor Course Description: David L Eaton

PHG 518 Computer Demonstrations in Genetic Epidemiology (2/4, max. 4) Karen Edwards
Demonstrations and use of computer programs designed specifically for analysis of genetic epidemiologic data, including heritability, segregation, and sib-pair linkage analysis. Discussions focus on interpretation of results. Laboratory sections apply methods to data provided by instructor. Offered: jointly with EPI 518; Sp.

PHG 519 Statistical Methods in Genetic Epidemiology (3)
Theory and application of statistical techniques used in genetic epidemiology. Includes discussion of association studies, linkages and segregation analyses. Examples stressed with reference to assumptions and limitations. Prerequisite: either BIOST 513 or BIOST 518; PHG 511/EPI 517; or permission of instructor. Offered: jointly with BIOST 516/EPI 516.

PHG 521 Culture, Society, and Genomics (3) McGrath
Examines social and cultural issues of human genome sequencing and control of genetic expression. Attitudes and behaviors toward health, illness, and disability are studied using historical, contemporary, and cross-cultural case study material. Offered: jointly with ANTH 574/NURS 582; Sp.
Instructor Course Description: Barbara B. Mcgrath

PHG 522 Ethical Frameworks for Public Health Genetics (3) Mastroianni
Application of ethical principles to problems in genetics practice, policy, and research. Includes: historical experiences with genetic screening and genetic engineering; application of ethical frameworks to emerging problems in public health genetics. Prerequisite: LAW H 504/B H 514/PHG 512, or permission of instructor. Offered: jointly with B H 516.
Instructor Course Description: Anna C. Mastroianni

PHG 523 Genetics and the Law (3) Kuszler, Mastroianni
Explores and analyzes legal issues arising from genetic technologies and information. Statutes, regulations, and cases demonstrate the constitutional, contract, tort, criminal, and family law use of genetic science to determine rights, disputes, and controversies. Prerequisite: LAW H 504/B H 514/PHG 512 or permission of instructor. Offered: jointly with LAW H 520; Sp.

PHG 525 Public Commentary on Ethical Issues in Health Genetics (3) Kelly Edwards
Explores issues in public health genetics through academic commentary, personal narratives, science fiction, and film using ethical frameworks from narrative ethics, feminist ethics, and principlism. Includes cloning, assisted reproduction, prenatal genetic testing, presymptomatic genetic testing, gene therapies, scientific responsibility, and GMOs. Graduate students only. Offered: jointly with B H 515; Sp.

PHG 536 Bioinformatics and Gene Sequence Analysis (3) Rose
Nature and relevance of molecular sequence information, computer-based protein, and DNA sequence analysis, molecular sequence and genomic databases, and methods for database accession and interrogation. Prerequisite: background in molecular biology and permission of instructor. Offered: jointly with MEBI 536/PABIO 536; Sp.
Instructor Course Description: Timothy M Rose

PHG 542 Genetic Discovery in Medicine and Public Health (3) Burke
Addresses the implications of genetic science for clinical and public health practice, with an emphasis on health policy and ethics. Offered: jointly with B H 530; W.

PHG 551 Human Genomics: Science, Ethics, and Society (3) Fullerton
Explores the ethical and social implications of human molecular genetics and genomics investigation. Recent research is critically evaluated for its potential impact on scientific practice, research participation, and societal understandings. Prerequisite: LAW H 504/B H 514/ PHG 512 or permission of instructor. Offered: jointly with B H 551/GENOME 573; A.

PHG 580 Interactive Seminar (1, max. 30) Lin
Seminar series on topics related to public health genetics, including current bioethical, legal, medical, biotechnology, and public policy issues. Credit/no-credit only. Offered: jointly with LAW H 579.

PHG 590 Selected Topics in Public Health Genetics (1-6, max. 6)
Tutorials are arranged for a small number of students for in-depth examination of an area of public health genetics, usually of a current nature.
Instructor Course Description: Kelly Fryer-Edwards

PHG 595 Master's Practicum (1-12, max. 12)
Supervised practice experience providing students an opportunity to learn how genetics is applied in a public health setting and in the formulation and application of public health policy. Prerequisite: practicum agreement.

PHG 600 Independent Study or Research (*-)
Credit/no-credit only.

PHG 700 Master's Thesis (*-)
Credit/no-credit only.

PHG 800 Doctoral Dissertation (*-)
Credit/no-credit only.