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Course Descriptions |
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Detailed course offerings (Time Schedule) are available for
To see the detailed Instructor Class Description, click on the underlined instructor name following the course description.
BIOEN 201 Bioengineering Tools (2) Thomas
Introduction to bioengineering; laboratory safety, acquisition and analysis, presentation tools for biomedical applications. Prerequisite: MATH 126; PHYS 121; corequisite: CSE 142; PHYS 122. Offered: W.
Instructor Course Description:
David G. Castner
BIOEN 299 Introduction to Bioengineering (1) Verdugo
Lectures on the various aspects of bioengineering; orientation in bioengineering studies and practice. Credit/no credit only. Offered: ASp.
Instructor Course Description:
Pedro Verdugo
BIOEN 301 Bioengineering Systems Analysis (4) Lewis, Neils, Pun
Investigates static and dynamic problems that are found in medicine and biology. Exposes real biomedical applications of first- and second-order differential equations. Analyzes current bioengineering and biomedical problems and make measurements of the systems that present those problems. Weekly laboratories. Prerequisite: BIOEN 201; CSE 142; PHYS 122; corequisite: BIOL 200; MATH 307. Offered: Sp.
BIOEN 302 Introduction to Biomedical Instrumentation (4) Folch, Neils
Introduces the theory of measurement and the practicalities of measurement of biological variables. Basic amplifier theory, discussion of noise in physical systems and its reduction. Uses actuators to test biomedical systems. Prerequisite: BIOEN 301; CSE 142; E E 215. Offered: A.
Instructor Course Description:
Albert Folch
BIOEN 303 Bioengineering Signal Processing (4) Gao, Li, Neils
Introduction of signal processing techniques necessary to record and analyze medical and biological data. Uses transform calculus to analyze differential equations and develop approximations to functions. Introduces sampling and applies it to biological data. Prerequisite: BIOEN 302; BIOEN 304. Offered: W.
BIOEN 304 Introduction to the Bioengineering Analysis of Physiology I (4) Sauro
Introduction of engineering analysis of physiological systems. Course covers cellular function through its control by the central nervous system. Prerequisite: BIOEN 301; CSE 142. Offered: A
BIOEN 305 Introduction to the Bioengineering Analysis of Physiology II (4) Regnier
Introduction to the cardiovascular system. Explores the cardiovascular system as an engineering system in which the heart is a pump, and the load and distribution of blood to organs on the heart depend on the demands of the system. Introduces principles of fluid transport. Prerequisite: BIOEN 302; BIOEN 304; co-requisite: either STAT 390, MATH 390, or IND E 315. Offered: W
Instructor Course Description:
Michael Regnier
BIOEN 357 Introduction to Molecular Bioengineering (4) Bryers
Introduces molecular bioengineering. Molecules as building blocks to engineer surfaces. Molecular therapeutics, drug delivery, diagnosis and biomaterials. Examines design principles for biomedical materials and devices. Prerequisite: BIOL 200; BIOEN 303; BIOEN 305; recommended: either CHEM 223, CHEM 237, or CHEM 335. Offered: Sp.
Instructor Course Description:
Cecilia Giachelli
James D Bryers
BIOEN 420 Medical Imaging (4) Yuan
Various medical imaging modalities (x-rays, CT, MRI, ultrasound, PET, SPECT, etc.) and their applications in medicine and biology. Extends basic concepts of signal processing (BIOEN 303) to the two and three dimensions relevant to imaging physics, image reconstruction, image processing, and visualization. Prerequisite: BIOEN 303; MATH 308; CSE 143. Offered: A.
BIOEN 440 Introduction to Biomechanics (4) Sanders
Presents the mechanical behavior of tissues in the body and the application to design of prostheses. Tissues studies include bone, skin, fascia, ligaments, tendons, heart valves, and blood vessels. Discussion of the structure of these tissues and their mechanical response to different loading configurations. An important part of the class is a final project. Offered: jointly with M E 445; Sp.
BIOEN 455 BioMEMS (4) Folch
Introduction to BioMEMS. State-of-the-art techniques in patterning biomolecules, machining three-dimensional microstructures and building microfluidic devices. Various biomedical problems that can be addressed with microfabrication technology and the engineering challenges associated with it. Biweekly labs. Prerequisite: BIOEN 303. Offered: W.
BIOEN 457 Advanced Molecular Bioengineering (4) Stayton
Fundamentals of molecular recognition: thermodynamics, forces, kinetics. Manipulation of recognition processes for current molecular bioengineering research and development. Fundamental physical chemistry of molecular recognition in the context of biomedicine. Therapeutics based on cells. Prerequisite: BIOEN 357; BIOC 405. Offered: Sp.
BIOEN 467 Biochemical Engineering (3) Baneyx
Application of basic chemical engineering principles to biochemical and biological process industries such as fermentation, enzyme technology, and biological waste treatment. Rapid overview of relevant microbiology, biochemistry, and molecular genetics. Design and analysis of biological reactors and product recovery operations. Prerequisite: either CHEM 223 with CHEM E 340 or either CHEM 237 or CHEM 335; recommended: CHEM E 465. Offered: jointly with CHEM E 467; Sp.
BIOEN 481 Bioengineering Design and Capstone Principles (4) Vaezy
Teaches design principles in bioengineering and guides the development of design-based senior capstone projects. Prerequisite: BIOEN 303; BIOEN 305. Offered: Sp.
Instructor Course Description:
Paul Yager
BIOEN 482 Bioengineering Capstone Project ([2-6]-, max. 8)
Independent senior design project. Prerequisite: BIOEN 357; BIOEN 481; corequisite: STAT 390. Offered: AWSpS.
BIOEN 485 Computational Bioengineering (4) Thomas, Vicini
Introduction to computational, mathematical and statistical approaches to the analysis of biological systems, including systems and control theory, molecular models and bioinformatics. Lectures and laboratory sessions emphasize practical problems in kinetics, metabolism and genomics. Prerequisite: CSE 143; BIOEN 305; MATH 308. Offered: A.
Instructor Course Description:
Paolo Vicini
Wendy Thomas
BIOEN 490 Engineering Materials for Biomedical Applications (3) Horbett
Combined application of principles of physical chemistry and biochemistry, materials engineering, to biomedical problems and products. Applications include implants and medical devices, drug delivery systems, cell culture processes, diagnostics, and bioseparations. Offered: jointly with CHEM E 490; A.
BIOEN 491 Controlled-Release Systems: Principles and Applications (3) Pun
Mechanisms for controlled release of active agents and the development of useful drug delivery systems for this purpose. Release mechanisms considered include diffusive, convective, and erosive driving forces. Delivery routes include topical, oral and in vivo. Some special case studies covered in detail. Offered: jointly with CHEM E 491; W.
Instructor Course Description:
Suzie H Pun
BIOEN 492 Surface Analysis (3) B. Ratner
Understanding of solid surfaces for research and development in microelectronics, catalysis, adhesion, biomaterials, science wear, and corrosion science. Newer methods available to study surfaces of materials. Electron emission spectroscopies (ESCA, Auger): ion scattering, ion spectroscopic, photon spectroscopic, and thermodynamic methods. Offered: jointly with CHEM E 458; Sp.
BIOEN 497 Bioengineering Education Outreach (1-2, max. 6)
Work with K-12 schools or community organizations. Current science education research and instructional techniques. May involve presentations or instruction in hands-on activities.
BIOEN 498 Special Topics (1-6, max, 15)
Topics of current interest in the field, offered as lectures, conferences, or laboratory. Offered: AWSpS.
Instructor Course Description:
Albert Folch
David G. Castner
Herbert M Sauro
BIOEN 499 Special Projects (1-6, max. 24)
Individual undergraduate bioengineering projects (research or independent study) under the supervision of an instructor. Credit/no credit only. Offered: AWSpS.
Instructor Course Description:
Albert Folch
David G. Castner
Herbert M Sauro
BIOEN 501 Molecular Bioengineering (4) Bryers
Examines advanced topics in molecular diffusion, reaction kinetics, and convective transport modeling as applied to biological systems. Includes mathematical analysis and numerical simulation techniques applied to: Non-Fickian diffusion, rotational versus translational diffusion, immobilized enzyme kinetics, drug release, and gene delivery. Offered: A.
Instructor Course Description:
James D Bryers
BIOEN 502 Cellular Bioengineering (4) Giachelli
Covers basic principles of cell biology (including cell structure, function, and signaling), recombinant RNA/DNA technology, and specific examples of cellular bioengineering applications including gene delivery, RNA silencing, and tissue engineering. Prerequisite: BIOEN 501. Offered: W.
BIOEN 503 Systems Bioengineering (4) Regnier, Vicini
Explores whole-body or organ physiology topics from an engineering perspective. Uses various model systems to elucidate engineering principles such as feedback control and homeostatic regulation. Includes real-world examples, computer modeling, and research design approaches. Prerequisite: BIOEN 502. Offered: Sp.
BIOEN 504 Introduction to Technology Commercialization (4)
Explores essential business, legal, engineering, and other skills necessary to take new technology from research to market. Covers intellectual property, market analysis, licensing, funding mechanisms such as venture capital, and product marketing.
BIOEN 505 Studies in Technology Commercialization (4)
Explores essential business, legal, engineering, and other skills necessary to take new technology from research to market. Covers intellectual property, market analysis, licensing, funding mechanisms such as venture capital, and product marketing; introduces strategic planning, management of commercialization effort. Prerequisite: BIOEN 504.
BIOEN 506 Applying Technology Commercialization (4)
Explores essential business, legal, engineering, and other skills necessary to take new technology from research to market. Covers intellectual property, market analysis, licensing, funding mechanisms such as venture capital, and product marketing, market feasibility analysis, and business plan development. Prerequisite: BIOEN 505.
BIOEN 508 Career Pathways in Academia (1.5) Stayton
Overviews academic career options and job search preparation. Evaluates academic institutions and faculty appointments, identifies components of the academic curriculum vitae, teaching and research statements, and introduces tenure and faculty issues. Offered: A; even years.
Instructor Course Description:
Paul E. Kinahan
BIOEN 509 Bioengineering Departmental Seminar (1, max. 16) Bassingthwaighte
Research review and discussions centered on demonstrating approaches and solving scientific problems. Seminar lectures led by faculty and visiting faculty in Bioengineering and related disciplines. Credit/no credit only. Offered: WSp.
Instructor Course Description:
James Bassingthwaighte
BIOEN 510 Bioengineering Seminars (1)
Introductory seminar for new graduate students; review of departmental research.
BIOEN 511 Biomaterials Seminar (1) Hoffman, Horbett, Ratner
Presentation of student research results. Credit/no credit only. Prerequisite: permission of instructor. Offered: jointly with CHEM E 511.
BIOEN 513 Current Topics in Cardiac Physiology (1, max. 3) Regnier
Current research in cardiac physiology. Student presentation and discussions of current research methodologies.
BIOEN 516 Medical Imaging Seminar (0)
Weekly seminars, presented by UW faculty members, researchers and graduate students from UW, other academic institutions, and industry, on image computing and medical imaging. Topics include digital video, image processing, computer graphics, video/image compression, image analysis, algorithms and systems, pattern recognition, multimedia computer architectures, and other applications. Credit/no credit only.
BIOEN 518 Nanotechnology Seminar (1, max. 18)
Emphasizes frontier research in nanoscience and nanotechnology and on intellectual interactions within the nanotechnology community. Presented by experts in the field, with most being from other institutions. Prerequisite: graduate standing and permission of instructor. Credit/No Credit only. Offered: jointly with CHEM 597; AWSp.
Instructor Course Description:
Mack H Carter
BIOEN 520 Orthopedic Biomechanics (4) Ching
Mechanical engineering applied to musculoskeletal system with emphasis on techniques in orthopedic surgery. Measurement of mechanical properties of tissues. mechanics of bone, soft tissue, and muscle, mechanics of upper extremity, spine, and lower extremity. Engineering in surgery, gait analysis, joint replacement, fracture fixation. Prerequisite: BIOEN 440.
Instructor Course Description:
Randal Preston Ching
BIOEN 522 Biomechanics of Soft Tissue (3) Sanders
Applies soft tissue biomechanics to medical research. Develops specific biomechanical questions and experiments to address those aims or hypotheses.
BIOEN 530 Cell Biology (4)
Introduces fundamental molecular processes occurring in organisms. Emphasizes structure and organization of prokaryotic and eukaryotic cells, DNA replication, gene expression and regulation, protein biochemistry, signal transduction, and the extracellular matrix. Case studies illustrate concepts and how improper functioning of these systems leads to disease. Corequisite: BIOEN 521.
BIOEN 531 Cell Biology Laboratory (2)
Introduces basic microbiological and molecular biological techniques as applied to: isolation and identification of non-pathogenic bacteria, gene cloning and transfection, PCR, and bacteriophage genetics. Introduces mammalian cell and tissue culture techniques. Emphasizes lab safety and proper record keeping. Corequisite: BIOEN 530.
BIOEN 532 Medical Device Design (4) Baker
Emphasizes human factors in the design and intellectual property of medical devices. Examines the useful and safe design of devices for patients, caregivers, physicians, technicians, and manufactures. Addresses the physical, mental, and environmental constraints which affect fitting a device to the human user. Considers design for the device's life cycle.
BIOEN 533 Regulatory Affairs for the Medical Device Industry (4)
Reviews the government oversight of medical device development and those laws and regulations that apply to development, testing, and production of the devices. Examines the responsibilities of a regulatory affairs specialists in companies.
BIOEN 534 Medical Device Commercialization (4)
Introduces practical skills and tools for commercializing medical device technologies. Topics include: entrepreneurship, funding models/sources, licensing options and product portfolio growth models, introduction to developing and delivering a business plan, building teams or integrating teams, market assessment, converting R&D to sales and distribution, manufacturing start up strategies, and project management.
Instructor Course Description:
Francis A Spelman
BIOEN 536 Biosensors (4)
Review of biosensors in use and under development, and their application in vivo and in vitro monitoring of humans.
BIOEN 537 Biomaterials and Biocompatibility (4)
Covers materials science and biology needed to appreciate the use of materials in medicine and biology. Subjects include an overview of applications, biocompatibility, biomaterials types and properties, bimolecular materials, protein adsorption, cells on biomaterials, diagnostics, smart materials, drug release, tissues engineering, biomechanics of medical devices, blood compatibility, and biosurfaces.
BIOEN 538 Medical Imaging Diagnostics (4)
Examines disease presentation and identification as seen in medical images; use of contrast enhancement methods in various image modalities; disease analysis, modern diagnostic imaging methods, and diagnostic indicators using various imaging techniques. Prerequisite: B STR 540; CONJ 585, or equivalent courses.
BIOEN 539 Clinical Diagnostics (4)
Covers major diagnostic methods such as physical examination, chemical analysis, and microbiological analysis. Covers diagnostic process; presentation of patient, evaluation, documentation, communication between specialties, diagnosis, therapy choice, and outcome measurements. Prerequisite: P BIO 508; P BIO 520.
BIOEN 540 Biosystem Identification (4) Vicini
Fundamentals of mathematical modeling in medicine and biology, Introduction to compartmental models: a priori, a priori identifiability. Data measurement error, parameter estimation. Maximum likelihood, least squares. Introduction to tracer-tracee models, pharmacokinetics, pharmacodynamics. Models to test hypotheses. Hands-on computer experience. Prerequisite: ordinary differential equations, introductory statistics, or permission of instructor.
BIOEN 542 Computer Simulation in Biology (3) Bassingthwaighte, Graham
Introduction to mathematical modeling of biological phenomena. Tutorial text explains how to derive equations for simple models and apply them to generate simulation data. Application topics include kinetics of biomolecular reactions and enzyme saturation, membrane transport, organismal predation, competition and growth, compartmental and spatially distributed models, physiological control systems, probabilistic models. Prerequisite: P BIO 405 and P BIO 406 or equivalent or permission of instructor.
BIOEN 550 Mass Transport and Exchange in Biological Systems (3) Bassingthwaighte
Review of basic mechanisms of transport; transport through vascular system and blood-tissue exchange processes in organs; integrated system analysis of closed systems and applications to physiological regulation, medical imaging, and pharmacokinetics. Prerequisite: calculus, introduction to differential equations; cardiovascular physiology; E E network analysis or systems analysis, chemical engineering transport.
Instructor Course Description:
James Bassingthwaighte
James D Bryers
BIOEN 552 Microfabrication and Microfluidics (3) Folch, Yager
Studies the use of 2- and 3-dimensional structures in research and biomaterials, cells, and complex liquids. Focuses on micropatterning of surfaces and microfluidic chemical analytical systems. Co-requisite: BIOEN 553.
BIOEN 553 Microfabrication and Microfluidics Laboratory (3) Folch, Yager
Studies the creation of 2- and 3-dimensional structures for use in research with biomaterials, cells, and complex liquids. Each student will fabricate at least one PDMS device and demonstrate its function.Credit/no credit only. Co-requisite: BIOEN 552.
BIOEN 555 Cellular and Molecular Biomechanics and Cell Function (3) Pollack
Examines basic mechanisms of cell function with emphasis on motion. Includes principles of physics and chemistry, building to organelle structure and function; gel-like nature of cell and critical role of cell water; streaming, motility, contraction, mitosis, transport, and other cell basics.
BIOEN 560 Ultrasound in Bioengineering (4) Vaezy
Fundamentals of ultrasonic generation, formation, reception, and treatment of absorption, scattering, and transmission. Conventional and new methodology. (A, B, T-M mode, imaging, Doppler, tissue characterization, and nonlinear effects.) Prerequisite: E E/M E 525 for nonbioengineering students or permission of instructor.
BIOEN 561 Biomedical Optics (4)
Advanced theories of optical and spectroscopic measurement with emphasis on biomedical laser applications. Laser principles, instrumentation, and current practice in various biomedical uses, covering such areas as medicine, surgery, and biology. Prerequisite: BIOEN 302 or equivalent, or permission of instructor.
BIOEN 562 Image-Guided Therapy (4) Vaezy
Explores the theory and practice of Image-Guided Therapy (IGT) in medicine; fundamentals of various imaging and therapeutic modalities and their capabilities and limitations in IGT systems; and clinical applications of IGT.
BIOEN 565 Nuclear Magnetic Resonance in Biomedicine (2)
Basic physics of nuclear magnetic resonance (NMR) imaging and spectroscopy are presented. Research applications of NMR in physiology and biochemistry are reviewed with emphasis on the brain. Grade based on written tests and small research paper. Prerequisite: permission of instructor. Offered: jointly with RADGY 550.
Instructor Course Description:
Todd L Richards
BIOEN 568 Image-Processing Computer Systems (4) Kim
Components of digital processing computer systems. Two-dimensional filtering and optimal filter design as well as basic image-processing operations. Selected advanced image-processing topics introduced. Individual student project. Prerequisite: permission of instructor. Offered: jointly with E E 568.
BIOEN 571 Polymeric Materials (3) B. Ratner
Relationships between configuration, conformation, molecular order, microstructure, properties of polymeric materials. Concepts relevant to tailoring polymer molecules and microstructures for specific applications. Interactions between polymers and their in-service environment. Characterization and processing techniques relevant to polymeric materials. Prerequisite: one semester or two quarters of organic chemistry. Offered: jointly with MSE 571.
BIOEN 573 Biosensors and Biomedical Sensing (3) Yager
In-depth overview of the principal types of biosensors. Topics include: how biological molecules are used in sensing, how the sensors operate, how different sensors compare, under what circumstances sensors can be useful, and the applicability of sensors to biomedical sensing. Prerequisite: BIOEN 436 or permission of instructor.
Instructor Course Description:
Paul Yager
BIOEN 576 Laboratory Techniques in Protein Engineering (4) Stayton
Practical introduction to fundamentals of recombinant DNA technology and protein engineering. Gene design, bacterial molecular biology, genetic engineering strategy. Laboratory project focused on making site-directed protein mutations. Techniques include the Polymerase Chain Reaction, DNA sequencing, DNA cutting/splicing, protein expression. Prerequisite: background in biochemistry or molecular biology or consent of instructor.
BIOEN 577 Cell and Protein Reaction with Foreign Materials (3) Horbett
Study of ways in which cell and protein interactions with foreign materials affect the biocompatibility of biomaterials. Description of the phenomenology and mechanisms of protein adsorption, mammalian cell adhesion, and cell receptor biology and of methods used to study these phenomena. Surface properties of materials discussed in context of the course. Prerequisite: permission of instructor.
BIOEN 578 Biomembranes (3) Yager
Develops an understanding of the molecular principles that underlie the self-assembly of surfactants into natural and model membranes; in particular, on the relationship between the chemical structure of lipid molecules and the three-dimensional aggregates that they form in water.
BIOEN 579 Host Response to Biomaterials (3) Giachelli
Basic cell and molecular biology of the pathologies associated with biomaterial implantation that limit bioprosthetic use, including hemostasis, infection, acute and chronic inflammation, wound healing and fibrosis, and structural alterations. Major methods for histological analysis of retrieved implants. Prerequisite: general biology, BIOEN 490 (may be taken concurrently) or permission of instructor.
Instructor Course Description:
Cecilia Giachelli
BIOEN 584 Computational and Integrative Bioengineering (4) Vicini
Advanced computational, mathematical, and statistical approaches to the analysis of biological systems, including molecular models, time series, fractal systems, population kinetic analysis, and stochastic simulation. Lectures and laboratory sessions emphasize practical problems in kinetic analysis, metabolism, and genomics. Final project, written and oral reports. Prerequisite: BIOEN 485.
BIOEN 586 Tissue Engineering (3) Giachelli, Horbett
Explores methods to restore or replace function in the cardiovascular, epithelial, urinary, nervous, skeletal, and other systems in the human body by use of constructs that contain living cells. Presents scaffold preparation, angiogenesis, and use of stem cells.
BIOEN 590 Advanced Topics in Biomaterials (3) Horbett
Major, controversial issues in application of synthetic materials to medical problems. Blood compatibility, bioadhesion, intraocular lenses, contact lenses, polyurethanes, biodegradation, protein adsorption, corrosion, bone fixation, new materials, artificial heart, medical device regulation. Prerequisite: BIOEN 490 or CHEM E 490. Offered: jointly with CHEM E 590.
BIOEN 592 Surface Analysis (3) B. Ratner
Understanding of solid surfaces for research and development in microelectronics, catalysis, adhesion, biomaterials science, wear and corrosion science. Newer methods available to study surfaces of materials. Electron emission spectroscopies (ESCA, Auger); ion scattering, ion spectroscopic, photon spectroscopic, and thermodynamic methods. Offered: jointly with CHEM E 558.
BIOEN 598 Research Rotation (1-10, max. 30)
Research rotation in the laboratories of core or adjunct faculty in the Department of Bioengineering. Credit/no credit only. Offered: AWSpS.
BIOEN 599 Special Topics in Bioengineering (1-6, max. 50)
Offered at a graduate level periodically by faculty members within the Department of Bioengineering; concerns areas of research activities with current and topical interest to bioengineers. Prerequisite: undergraduate or graduate courses (or equivalent) determined individually for each special topic.
Instructor Course Description:
David G. Castner
Cecilia Giachelli
James D Bryers
John R. Overbeck
Wendy Thomas
Xiaohu Gao
Xingde Li
BIOEN 600 Independent Study or Research (*)
Credit/no credit only. Offered: AWSpS.
BIOEN 700 Master's Thesis (*)
Credit/no credit only. Offered: AWSpS.
BIOEN 800 Doctoral Dissertation (*)
Credit/no credit only. Offered: AWSpS.