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Instructor Class Description

Time Schedule:

Edward J Kelly
BIOEN 599
Seattle Campus

Special Topics in Bioengineering

Offered at a graduate level periodically by faculty members within the Department of Bioengineering; concerns areas of research activities with current and topical interest to bioengineers. Prerequisite: undergraduate or graduate courses (or equivalent) determined individually for each special topic.

Class description

Basic principles of pharmacokinetics and their application to the clinical setting, including: single-dose intravenous and oral kinetics, multiple dosing, nonlinear pharmacokinetics, metabolite kinetics, pharmacogenetics, and the role of disease in drug clearance and dose requirements, and kinetics of drug-drug interactions.

Student learning goals

Understand basic principles of pharmacokinetics; linear and non-linear Understand Pharmacokinetic-Pharmacodynamic relationships Define drug-drug interactions and the role of metabolites in safety testing Explain the role of variables (genetic, age, disease) on pharmacokinetics Operation of pharmacokinetic software packages

General method of instruction

Didactic with alternating class room and online instruction. There will also be a series of laboratory classes using PK software packages.

Recommended preparation

Class assignments and grading

There will be two take home midterm exams and a final course presentation.


The information above is intended to be helpful in choosing courses. Because the instructor may further develop his/her plans for this course, its characteristics are subject to change without notice. In most cases, the official course syllabus will be distributed on the first day of class.
Last Update by Edward J Kelly
Date: 09/17/2010