Search | Directories | Reference Tools
UW Home > Discover UW > Student Guide > Course Catalog 

Instructor Class Description

Time Schedule:

Rodney J.Y. Ho
PCEUT 586
Seattle Campus

Biotechnology and Biopharmaceutics

Current topics in pharmaceuticals and biotechnology focusing on transforming small molecules, proteins, and genes into therapeutic products. Includes new drug therapies, drug design, pharmacogenomics, molecular modeling, high throughput screen, production and stability considerations, and delivery systems of protein and gene therapeutics in relation to pharmacokinetic and therapeutic responses.

Class description

Recent introduction of genetically engineered peptide and protein pharmaceuticals necessitates the integration of a biotechnology course into the undergraduate and graduate curriculum. This elective course focuses on the application of biotechnology in developing protein pharmaceuticals. Although some existing courses briefly discuss the use of a limited number of protein pharmaceuticals, none systematically addresses the process of development and application of this class of drugs.

This course is designed to introduce basic principles of biotechnology and their applications in designing therapeutic products, with emphasis on research and development of biopharmaceuticals. Consideration will be given to molecular cloning, production, physical stability, and delivery systems of protein therapeutics in relation to their pharmacokinetic and therapeutic responses.

Student learning goals

* To introduce concepts/tools used in developing biotherapeutic agents.

* To gain a better understanding of toxicity and stability issues associated with biotech products.

* To understand the apparently similar, but unique biotech drugs that are in development or currently used.

* To gain a basic knowledge enabling one to critically evaluate pharmacokinetic and pharmacodynamic study results of these drugs.

* To expose students to the state-of-the-art therapeutics strategies in development/clinical trials.

General method of instruction

Lectures and discussion

Recommended preparation

Recommended Textbook - Biotechnology and Biopharmaceuticals: Transforming Protein and Genes into Drugs, Rodney J.Y. Ho and Milo Gibaldi (Available in HSL Reference Section)

There will be some other outside reading assignments. Students are expected to learn to integrate the material and discuss it in class.

Class assignments and grading

For C/NR 2 credits—Students will write a self-assessment (1-2 page) summarizing what they’ve learned from the course.

For 3 graded credits—Students will perform a literature research based on topics discussed in the class, write a short summary report and present to the class.


The information above is intended to be helpful in choosing courses. Because the instructor may further develop his/her plans for this course, its characteristics are subject to change without notice. In most cases, the official course syllabus will be distributed on the first day of class.
Last Update by Rodney J.Y. Ho
Date: 03/13/2007