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Instructor Class Description

Time Schedule:

Michael G. Yost
ENV H 551
Seattle Campus

Principles of Human Exposure Science

Examination of the scientific principles and methods used to characterize human exposures to environmental disease agents, discuss sources and pathways of exposure, use of standard factors, analytical approaches for exposure data, exposure biomarkers, and the energetics of physical agents and injuries. Prerequisite: CHEM 162; MATH 124. Offered: A.

Class description

Description. Exposure assessment science plays a critical role in risk assessment, epidemiology, and environmental public health interventions. This course provides an overview of the principles of exposure science and an examination of how these principles are applied to characterize the hazards of chemical and physical disease agents in both occupational and community environments. The course is divided into four modules: exposure pathway analysis, exposure data analysis, biological markers of exposure, and the energetics of physical agents and injuries.

Student learning goals

Describe the major and minor exposure pathways for occupational and environmental disease agents

Define the relationship between exposure and dose for the dermal, oral, and respiratory routes of exposure

Identify the major occupational and environmental health regulations in the United States that require exposure assessment data

Distinguish between exposure assessment strategies used for epidemiology, risk assessment, and environmental public health interventions

Describe the strengths and limitations of exposure data collected through self-reports, micro-environmental measurement methods, and personal monitoring methods

Characterize an exposure dataset with statistical descriptors

General method of instruction

Lecture, readings and short papers

Recommended preparation

Background knowledge of biology, physiology, chemistry, physics and biostatistics.

Class assignments and grading

Readings from the assigned text or other papers; Short answer problems, and 5-10 page written assignments

Problem sets, midterm, papers and final exam.


The information above is intended to be helpful in choosing courses. Because the instructor may further develop his/her plans for this course, its characteristics are subject to change without notice. In most cases, the official course syllabus will be distributed on the first day of class.
Last Update by Michael G. Yost
Date: 09/15/2008