B CUSP 237
First course for students planning to take three quarters of organic chemistry. Structure, nomenclature, reactions, and synthesis of the main types of organic compounds. No organic laboratory accompanies this course. Prerequisite: minimum grade of 1.7 in B CUSP 162.
This course focuses on the fundamental study of the chemistry of carbon, including its hybridization, structure, and shape, as well as the functional groups of organic chemistry, conformational analysis, stereochemistry, and an extensive study of nucleophilic substitution and elimination reactions. Coverage will also include the study of the chemistry and reactivity of the alkanes, alkenes, alchohols, alkyl halides, and alkynes. The purchase of a molecular models set is strongly recommended.
Student learning goals
Know the elementary concepts of carbon including its atomic structure, electron configuration, hybridization, along with its structure and shape when bonded. Constantly apply the concepts of general chemistry such as bonding and Lewis structures, bond dissociation energies, combustion reactions, isomerism, oxidation-reduction and acid-base reactions towards understanding the concepts related to carbon.
Learn the various functional groups that categorize the organic compounds, by recognizing their presence in the structures of simple and complex molecules. Constantly draw the structures of compounds with the appropriate functional groups and make models of them so as to acquire greater familiarity.
Apply the IUPAC rules of nomenclature to name the compounds correctly and be able to draw their proper structures, including the stereochemical features from their given names. Understand the relationship between structure and properties of various compounds, and be able to predict the properties of the various classes of organic compounds based upon their structure and the intermolecular forces of attraction displayed by them.
Know the process of writing stepwise mechanisms of the reactions of organic compounds by displaying the proper movement of electrons from one species to another. Apply “curved mechanistic arrows” to display electron motion during the mechanisms, and confidently draw correct structures showing unshared electrons and any formal charges on the pertinent atoms.
Know the concepts of stereochemistry, including recognizing and determining the number of asymmetric carbon atoms, enantiomers, diastereomers, Fisher Projection formulas, along with the applications of stereochemistry towards the reactions of compounds. Employ and build models to distinguish between structural isomers and the various types of stereoisomers.
Thoroughly explore and learn the concepts of nucleophilic substitution and elimination in context of reaction mechanisms, stereochemistry, reaction-order, as well as the distribution and the types of products. Be able to confidently apply these concepts when solving reactions, writing mechanisms, and rationalizing the distribution of products. Develop a complete understanding and mastery of the reactions of the various classes of organic compounds, by being able to write the structures of any missing reactants, reagents, and products either with or without the aid of a reaction mechanism.
General method of instruction
Classroom instruction with student participation and engagment that includes the use of overhead slides and tranparencies, molecular models that help visualize the structure, as well as course and lecture handouts.
Prerequisite: Minimum grade of 1.7 in B CUSP 162.
Students should be able to confidently apply the concepts learnt in the three-quarter general chemistry course sequence so as to develop a better understanding of the structure, bonding, and reaction characteristics of carbon and organic compounds.
Class assignments and grading
Quizzes and Exams. Practice problem sets (not graded) but which provide additional practice of solving problems and learning the concepts will also be administered.
Student competency and performance on all the graded assignments of the course.