UW Research

Histology and Imaging Core (HIC)



Research histopathology service


To provide researchers fee-for-service access to expertise and state of the art instrumentation across a broad range of services including; routine histology, immunohistochemistry, microscopy, digital imaging and quantitative digital pathology, cell based multiplex assays and comparative pathology consultation.

This core is open to all investigators, including; UW and their affiliates, commercial and not-for-profit biotechnology companies, and other academic institutions.

Type: Equipment/Services


  • Routine histology including tissue processing and embedding (paraffin and OCT cryopreservation).
  • Slide cutting and staining (H&E as well as affinity based histochemical (special stains).
  • Immunohistochemistry, including antibody optimization and validation as well as consultation on staining strategy and antibody selection.
  • Whole slide scanning, image analysis and stereology
  • Conventional upright brightfield and fluorescent microscopy and image acquisition
  • Luminex Cell Based Multiplex Assay
  • Comparative Pathology Consultation from board certified Veterinary Pathologists


  • Leica Bond
  • Hamamatsu Nanozoomer Digital Pathology
  • Visiopharm Integrator Software
  • Nikon 90i upright research microscope
  • Luminex Bio-Plex 200
  • Deltavision Elite microscope

Keywords: General

Histology, Immunohistochemistry, Immunofluorescence, Digital Imaging, Quantitative Digital Pathology

Keywords: Specific

Histopathology, fixation, tissue processing, paraffin embedding, paraffin sectioning, frozen sections, cyrosections, IHC, antibodies, multiplexing, whole slide scanning, image analysis, stereology, Leica Bond, Visiopharm, Nanozoomer