The Bioanalytical Pharmacy Core (the Core) serves the general research community at UW, the Fred Hutchinson Cancer Research Center, and regional biotechnology companies on a cost-per-use basis. This resource, which is administered within the Department of Medicinal Chemistry at The University of Washington, provides biophysical instrumentation and expertise for the characterization of molecular interactions between biotherapeutic molecules and their receptors, metabolites, delivery vehicles, or any relevant biological components.
The specific aims for the Center include development of delivery platforms that enhance the efficiency of therapeutic proteins, peptides, and siRNA to reach the cytosolic compartment of cells. The biophysical core facility provides analytical expertise in several state-of-the-art biophysical methods including analytical ultracentrifugation, surface plasmon resonance, differential scanning calorimetry, and isothermal titrating calorimetry. Interested labs can submit samples for Core scientists to run. The Core also provides training to CIDB and UW students and staff. The Core is funded through the Center for Intracellular Delivery of Biologics (CIDB), which is administered in the Department of Bioengineering.
Core Services Offered
We provide biophysical instrumentation and expertise for the characterization of molecular interactions between biotherapeutic molecules and their receptors, metabolites, delivery vehicles, or any relevant biological components. http://depts.washington.edu/cidb4bio/index.shtml
Life Science Discovery Fund (LSDF), 2010-2013
Patrick Stayton, College of Engineering, Department of Bioengineering
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