UW Research

FAQs: Intended Research


What is a hESC-like line?
A cell that can generate all three embryonic germ layers. Embryonic stem cells or “ESC” are defined in GIM-36 as “an undifferentiated, pluripotent stem cell, typically derived from an embryo.” Cells that resemble ESCs but were induced by transformation with specific genes or drugs are pluripotent. Since induced pluripotent cells act like stem cells but were not derived from embryos, they are called “hESC-like”.