Gastroenterology and Hepatology Faculty Research

The Gastroenterology and Hepatology faculty are locally and nationally recognized for their research, which focuses on the pathogenesis and treatment of pediatric gastrointestinal and hepatic diseases. Our research program has had consistent NIH/NIDDK and corporate funding for over 20 years, and continues to grow in breadth and funding. Within our division, the main areas of focus include:

  1. the pathogenesis, progression, and treatment of pediatric genetic cholestatic liver diseases including biliary atresia, progressive familial intrahepatic cholestasis, alpha-1-anti trypsin deficiency, and bile acid deficiency;
  2. the epidemiology, pathogenesis, and treatment of chronic viral hepatitis B and C;
  3. The pathogenesis and treatment of non-alcoholic steatohepatitis;
  4. Early diagnosis for Cystic Fibrosis Liver Disease
  5. novel treatments for inflammatory bowel disease (IBD);
  6. the epidemiology and genetics of recurrent and chronic pancreatitis;
  7. fecal microbiota transplantation in inflammatory bowel disease and for recurrent or chronic Clostridium difficile infection;
  8. enteral nutrition therapies in inflammatory bowel disease;
  9. the pathogenesis and treatment of intestinal failure;
  10. outcome disparities in liver transplantation;
  11. indicators of medical frailty among patients listed for liver transplant and
  12. the hepatocellular mechanisms and molecular toxicology behind the hepatotoxicity of many widely-used medicinal herbs.
  13. Rectal function after surgery for Hirschsprungs Disease