HMC Department of Surgery

The University of Washington is one of the largest, best supported, and most productive research universities. Our residents and fellows have access to a broad spectrum of outstanding research.

Harborview Research Personnel

Hikmatullah Arif   Research Study Coordinator, Trauma
Austin Bailey Research Assistant, Burn
Claudia Baker Research Assistant, Burn
Elizabeth Barnes Research Assistant, Trauma
Gretchen Carrougher RN, MN  NIDILRR Research Nurse Supervisor
Emily Eschelbach, RN Research Nurse, Burn
Iris Garcia  Manager of Program Operations, Research
Wendy Hamar  Research Coordinator, Vascular
Laura Hennessy, RN  Research Nurse Supervisor, Trauma
Mahrukh Kadri Research Assistant, Trauma
Brenda Allen-Kline, RN Research Nurse, Vascular
Patricia Klotz, RN Research Nurse Supervisor, Trauma
Stephen Sibbett Research Technoloist, Gibran Lab
Keegan Stromberg Research Assistant, Trauma

Clinical Trials

Research projects are organized by PI and their respective Section Membership. HIPRC Faculty may belong to multiple Sections.






Saman Arbabi


A Prospective Randomized Prehospital Double-blind, Placebo Controlled Pilot Trial Comparing Kcentra plus Standard of Care to Placebo plus Standard of Care in Trauma Patients with Hemorrhagic Shock

This study evaluates the feasibility of the EMS to identify patients in shock and the ability to package, store and administer Kcentra in the field.  It also evaluates the safety and efficacy of Kcentra, a four factor prothrombin complex, as an alternative to plasma transfusion.

Eileen Bulger


Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Study of AB103 as Compared to Placebo in Patients with Necrotizing Soft Tissue Infections

This a pivotal Phase 3 clinical trial that investigates the efficacy and safety of AB103, an investigational drug, for the treatment of NSTI.

Eileen Bulger


Physiologic signals and signatures with the Accuryn Monitoring System in Intensive Care Patients

This is an observational study of physiologic signals using the Accuryn urinary drainage monitoring system.

Nicole Gibran


A Multicenter, Multinational, randomized, controlled, assessor blinded study, performed subjects with thermal burns, to evaluate the efficacy and safety of NexoBriod compared to Gel Vehicle and compared to Standard of Care

This is a Phase 3 clinical trial to evaluate the efficacy and safety of enzymatic eschar removal with NexoBrid as compared to Gel Vehicle and standard of care.

Samuel Mandell


The RE-ENERGIZE Study: A Randomized Trial of Enteral Glutamine to Minimize Thermal Injury

This double-blinded clinical trial looks to examine what is the effect of patient specific dosages of enteral glutamine, a protein supplement, on 6 month mortality in severely burned patients.

Tam Pham


Protective Effects of Propranolol in the Severely Burn Patient: A Safety and Efficacy Trial

This prospective multicenter randomized efficacy and safety trial examines the physiologic effects and safety of propranolol administered to adult patients with severe burn injury. In addition, this study looks to identify which subpopulations may be most likely to benefit from propranolol treatment, and to identify safe and effective propranolol dosing levels.

Tam Pham


Burn Navigator:  Evaluation of the Effectiveness of the Burn Navigator in Improving Resuscitation Outcomes

This proposal will test the ability of a new FDA-cleared computerized burn resuscitation system (Burn Navigator) to improve burn resuscitation and monitoring.

Tam Pham


Peds Nexobrid:  A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid as compared to standard of care (SOC) treatment

This study is a multi-center trial to evaluate the efficacy and safety of Nexobrid, a non-surgical eschar removal treatment over Standard of Care (SOC) treatment of thermal burns in children.

Tam Pham


Avita RECELL:   A Prospective Multicenter Randomized Controlled Clinical Study to Investigate the Safety and Effectiveness of RES (Regenerative Epidermal Suspension) Prepared with the RECELL® Device Compared to Conventional Care for Healing of Donor Sites in Infants, Children and Adolescents (Aged 1–16 Years)

This is a trial to investigate whether autologous skin cell suspension prepared with the RECELL device (i.e., RES) can be safely and effectively used to promote healing of study donor sites created for sourcing tissue during treatment of skin defects requiring autografting.

Bryce Robinson


Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Safety and Efficacy of Reltecimod as Compared to Placebo in Addition to Standard of Care in Patients with Sepsis-associated Acute Kidney Injury

This is a Phase 3 clinical trial to evaluate the safety and efficacy of Reltecimod, a CD28 antagonist, in attenuating the inflammatory response in patients with sepsis-associated acute kidney injury.


Research Studies


PI Department Project
Eileen Bulger Surgery Therapeutic Limb Cooling to Prevent Amputation in Prolonged Damage control Resuscitation
Eileen Bulger Surgery Development of a National Trauma Research Action Plan
Joseph Cuschieri Surgery A comparison of Google Glass and traditional video vantage points for bedside procedural skill assessment

Joseph Cuschieri


Prevention of Clots in Orthopaedic Trauma (PREVENT CLOT):  A Randomized Pragmatic Trial comparing the complications and Safety of Blood Clot Prevention Medicines Used in Orthopaedic Trauma Patients  (Co-PI)
Nicole Gibran Surgery Surgical Wound Repair:  fibroproliferative responses to cutaneous injury
Ronald Maier Surgery Improving Outcome in Ischemia and Ischemia Reperfusion Injury Using Elemental Reducing Agents
Charles Mock Surgery Injury Prevention in Ghana
Grant O’Keefe Surgery Protein-enhanced enteral nutrition and metabolomics in critically ill trauma and surgical patients
Grant O’Keefe Orthopaedics A multi-center, prospective observational study to evaluate the use of Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE STUDY) (Co-PI)


Recent Publications