Undergraduate Research Program

Mackenzie Croy

Croy, Mackenzie
Major: Molecular, Cellular and Developmental Biology
Mentor: Bonny Brewer,Genome Sciences

Contact: mcroy@uw.edu

Current research project: Investigating Replication Stress in the Highly Repetitive rDNA Region of Budding Yeast



Translate your work so that we can all understand its importance
I use yeast as a model organism to study a genetic mutation that causes dwarfism in humans. Areas all along the DNA called origins of replication recruit proteins and initiate DNA synthesis. A highly repetitive region of these origins is found in the rDNA locus and is used to encode ribosomes to synthesize proteins. I manipulate factors involved in this process in order to better understand the mechanisms of DNA replication.

What is the most exciting and/or rewarding aspect of your undergraduate research experience?
My favorite part of my undergraduate research experience has been the practical application of the things I learn in my classes. I love getting to incorporate the knowledge I get from my Biology coursework and tying it into the research I do in lab. It has been amazing to learn more about myself and what I can accomplish when I’m passionate about the work I do. Undergraduate research has helped me take what I’ve learned in class and apply it to real-world problems in research.

What advice would you give a student who is considering getting involved in undergraduate research?
If any student is interested in undergraduate research I would tell them to visit the Undergraduate Research Program and go for it! Undergraduate research is a great way to get involved and get to know faculty in any department.