Undergraduate Research Program

Emily Huebner

Biochemistry        Minor: Chemistry
Mentor: Roland Walter, Hematology-Oncology

Contact: huebnem@uw.edu

Current research project: A Phase 1/2 Trial of G-CSF, Cladribine, Cytarabine, and Dose-Escalated Mitoxantrone (G-CLAM) in Adults with Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS)



Translate your work so that we can all understand its importance
I am studying the effects and safety of new chemotherapy regimens for acute myeloid leukemia through clinical trials with the goal of improving long term patient survival and replacing the current standard of therapy. Because the use of a set of criteria to determine trial eligibility restricts the amount of patients we can treat on the clinical trials (also called being on-protocol), we are also treating patient populations outside of the clinical trials (also called off-protocol) with the same treatment. The purpose of this is to assess whether the exclusion criteria introduces a potential bias into the results of the studies and whether the use of clinical trials accurately represents the population at large.

What is the most exciting and/or rewarding aspect of your undergraduate research experience?
Through this opportunity I have gained knowledge of medical terminology through the complex vocabulary in patient charts, discovered how to interpret hematopathology reports and cytogenetics test results, and gained a better understanding of the physiology and morphology of acute myeloid leukemia. This position gave me the opportunity to put into practice the material I’ve learned in classes, and lay the foundation for my future study of hematology-oncology that I will learn medical school.

What advice would you give a student who is considering getting involved in undergraduate research?
Undergraduate research is the best opportunity to connect classroom learning to real world application. It equips students to start with an idea, come up with a method of research to study that idea, and how to interpret the results of their study.