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Undergraduate Research Program

Aaron Bi Rosen

Biochemistry          Minor: Chemistry, Applied Math
Mentor: Heather Mefford, Pediatrics; Candace Myers, Pediatrics


Current research project: Exome Guided Gene Discovery in Epileptic Encephalopathies



Translate your work so that we can all understand its importance
Epileptic Encephalopathies (EEs) are severe, early onset seizure disorders caused by aberrant electrical activity in the brain, often accompanied by developmental delays. Deleterious changes to the protein coding regions of the genome (exome) have been implicated as causes of EEs and my research utilizes a variety of tools in molecular biology to detect and evaluate this variation.

What is the most exciting and/or rewarding aspect of your undergraduate research experience?
The most rewarding aspect of my experience is the opportunity to learn and grow as a researcher under the guidance of accomplished scientists. Joining the Mefford Lab gave me more than an opportunity to make meaningful contributions – it gave me a community of role models. Effort does not always pay off in success, but it always brings experiential knowledge and I am grateful for the privilege to pursue understanding in such an exciting field.

What advice would you give a student who is considering getting involved in undergraduate research?
Take a leap of faith on an experience that sounds interesting to you and persevere! The UW is an enormous research university with countless opportunities for undergraduates.