Danny D Shen
Covers the fundamentals of pharmacokinetics. Includes lectures and laboratory exercises on the key concepts in pharmacokinetics, including compartmental kinetics, clearance, protein binding, bioavailability, pharmacodynamics, clinical pharmacokinentics, and Michaelis-Menten kinetics.
This is an intermediate level course in fundamentals of pharmacokinetics, and is intended to bridge the gap between the undergraduate (PCEUT 405) and advanced graduate (PCEUT 501-2) course offering in this area. There will be in-depth discussion on the key concepts in pharmacokinetics, including compartmental kinetics, clearance, multiple dosing, plasma protein binding, bioavailability and first-pass, metabolite kinetics, pharmacodynamics, and Michaelis-Menten kinetics.
Student learning goals
General method of instruction
Concepts will be reviewed and discussed through a question-and-answer format.
PCEUT 405 or an equivalent in basic pharmacokinetics is a pre-requisite to this course.
Class assignments and grading
Assigned text readings before class.
There will be a mid-term written exam and a comprehensive final oral exam.