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Instructor Class Description

Time Schedule:

Jaisri Lingappa
PABIO 581
Seattle Campus

Current Literature in Pathobiology

Develops skills in analyzing data and assessing conclusions through an analysis of current literature in pathobiology. Focuses on breadth and analytical skills. Prerequisite: enrollment in the pathobiology graduate program.

Class description

This year's literature review is entitled "Classic Papers in the History of Molecular Biology". Each week, the instructor will assign one or two classic papers from the primary literature in molecular biology, often related to Nobel prize winning studies. Recommended reading will include reviews and commentaries that will add to studentsí understanding of the history and the science. Each class will begin with two short student presentations (5 min each), assigned in advance, followed by a 40 minute discussion of the papers and their scientific and historical context. Students will also be asked to choose one class in which they will do extra reading to be able to answer questions that arise during discussions.

Student learning goals

At the end of this course, you should be able to describe experiments that led to important discoveries in the history of molecular biology.

At the end of this course, you should be able to explain why these discoveries were breakthroughs, given the scientific understanding at that time.

At the end of this course, you should be able to explai the implications of these breakthroughs for later discoveries and for pathogen biology in the modern era.

You will also gain experience in presenting and discussing primary literature.

General method of instruction

All classes will be in a discussion format, with short presentations by students at the beginning of class.

Recommended preparation

Students should be graduate students enrolled in the Pathobiology graduate program or another biological science graduate program.

Class assignments and grading

Students will be asked sign up to do either a short presentation that summarizes the primary papers for discussion or a short presentation that puts the work in historical and biological context. Students will also be asked to choose one class in which they will do extra reading to be able to answer questions that arise during discussions.

This course is graded as CR vs. NC. Students will receive full credit if they participate to a reasonable extent.


The information above is intended to be helpful in choosing courses. Because the instructor may further develop his/her plans for this course, its characteristics are subject to change without notice. In most cases, the official course syllabus will be distributed on the first day of class.
Course Website
Last Update by Jaisri Lingappa
Date: 09/23/2013