Time Schedule:
Michael J Gale
IMMUN 441
Seattle Campus
General properties of immune responses; cells and tissues of immune system; lymphocyte activation and specificity; effector mechanisms; immunity to microbes; immunodeficiency and AIDS; autoimmune diseases; transplantation. Prerequisite: either BIOL 220 or BIOL 202; may not be repeated; recommended: GENET 371, GENET 372, BIOC 405, or BIOC 440. Offered: jointly with MICROM 441; A.
Class description
For questions about registration in Immunology 441 or Microbiology 441, please contact Peggy McCune (staff support) at pmccune@u.washington.edu. We will cover the general properties and differentiation of the bone marrow-derived cells that comprise the immune system and describe the tissues in which they mature, the genetics and protein structure of the receptors used by immune cells to recognize foreign molecules, the pathways by which these foreign substances are processed for recognition by immune cells, the chemical mediators of many immune functions, and clinical aspects of immunity, including resistance to pathogens, transplant rejection, hypersensitivity, autoimmunity, and AIDS.
Student learning goals
General method of instruction
Co-chairs for the AUT/2008 course are Dr. Joan Goverman and Dr. Michael Gale, both of whom will lecture as well as organize the course. Other Immunology faculty members also lecture, providing their expertise in special areas of Immunology.
Recommended preparation
The course will consist of three weekly lectures given by a variety of experts in the field and a required discussion (Quiz) section taught by graduate students in immunology.
Class assignments and grading
TEXTBOOK - Janeway’s Immunobiology, 7th Edition (Garland Press), by Kenneth M. Murphy, Paul Travers, Mark Walport, ISBN Paperback: 978-0-8153-4123-9,Packaged with a CD-ROM Reading assignments will be mainly confined to the textbook and are meant to support the lecture material.
Grades will be assigned on the basis of performance on three equally weighted exams -- two midterms and a final exam. Quiz sections will include weekly non-graded quizzes.
