Kendall M Gray
Molecular genetics: description of fundamental genetics processes such as mutation, repair, genetic exchange, recombination, and gene expression. Use of genetic strategies to analyze complex biological processes. Focus is on prokaryotic organisms. Prerequisite: BIOL 200; either CHEM 223, CHEM 237, or CHEM 335. Offered: jointly with MICROM 411; W.
Microm / Genome 411 covers fundamental genetic processes such as mutation, repair, genetic exchange, recombination, and the regulation of gene expression. Lectures focus on the use of genetic strategies to analyze complex biological processes, with a major emphasis on problem solving. Laboratories allow students to apply principles and reasoning skills learned in lecture toward the isolation and characterization of novel bacterial mutants.
Student learning goals
General method of instruction
Class meets for 2 hours of lecture three days per week (MWF), with one of those periods typically devoted to laboratory topics. The laboratory operates on an open format in which the lab room is available for use from 10:00 until 4:30 daily (MTuWThF) on a drop-in basis. Students work in pairs and are required to come in daily to work on ongoing experiments. Laboratory work usually requires less than 30 minutes per day, although some procedures may take significantly longer.
Class assignments and grading
A single grade is given for both the lecture and laboratory combined. Grades are based on experimental write-ups (worksheets) from the laboratory exercises and four lecture examinations. There is no final exam for the course. Lecture exams are short answer format, with questions focusing on the application of principles covered in lecture and lab toward the solution of new problems.