Gregory J. Crowther
Supervised readings and group discussion. Prerequisite: minimum grade of 2.0 in either BIOL 350, BIOL 354, BIOL 355, BIOL 356, BIOC 405, BIOC 406, BIOC 440, BIOC 441, or BIOC 442.
The process of creating new therapeutics is rife with biology-related challenges, from identifying appropriate molecular targets to optimizing a compoundís pharmacokinetic properties. In this seminar course we will explore several of these challenges through extensive reading and discussion of primary research literature. Whenever possible we will draw examples from the field of malaria research, as this disease continues to inflict enormous morbidity and mortality upon humans and remains an area of considerable research activity worldwide. The course will meet twice per week; most class time will be devoted to discussions of research papers from the primary literature.
Student learning goals
(1) Gain willingness and confidence in reading and discussing primary research literature.
(2) Get better at reading, understanding, and discussing primary research literature.
(3) Gain an improved understanding of how research leads to the creation of new drugs for infectious diseases.
General method of instruction
Class assignments and grading
Homework/worksheets (20% of grade); classroom participation (20% of grade); short quizzes (20% of grade); leadership of 1 class session (20% of grade); independent projects (20% of grade).