Pathbreakers

A Century of Excellence in Science and
Technology at the University of Washington


UW Home Table of Contents

Researched and Compiled by Deborah L. Illman

Series Editor
Alvin L. Kwiram
Vice Provost for Research

Statue of George Washington at sunset
ONE HUNDRED YEARS AGO, THE REGENTS OF THE UNIVERSITY OF WASHINGTON RESOLVED:

"That we also indicate to the members of the Faculty our desire that each member of the Faculty endeavor to themselves perform some original work such as inventing, discovery or writing, in their respective departments."

-- From an 1895 resolution by the Board of Regents
shortly after they moved to the present campus


WE SHALL NOT CEASE FROM EXPLORATION
AND THE END OF ALL OUR EXPLORING
WILL BE TO ARRIVE WHERE WE STARTED
AND KNOW THE PLACE FOR THE FIRST TIME.
THROUGH THE UNKNOWN, REMEMBERED GATE
WHEN THE LAST OF EARTH LEFT TO DISCOVER
IS THAT WHICH WAS THE BEGINNING;
AT THE SOURCE OF THE LONGEST RIVER
THE VOICE OF THE HIDDEN WATERFALL
AND THE CHILDREN IN THE APPLE-TREE
NOT KNOWN, BECAUSE NOT LOOKED FOR
BUT HEARD, HALF-HEARD, IN THE STILLNESS
BETWEEN TWO WAVES OF THE SEA.

-- T. S. Eliot, from Four Quartets


Electron micrograph of abalone shell
EVERY GREAT ADVANCE IN SCIENCE HAS ISSUED FROM A NEW AUDACITY OF IMAGINATION.

-- John Dewey (1859-1952),
from The Quest for Certainty (1929)

Table of Contents

Foreword by President Richard L. McCormick

Introduction by Alvin L. Kwiram

Acknowledgments

1882
Orson Bennett Johnson, the Young Naturalists, and the Birth of a Museum

1901
Trevor Kincaid

1904
Birth of the Friday Harbor Laboratories
Early Industrial Chemistry Program Serves Regional Industry
Early Electrical Engineering at the University of Washington

1907
The Birth of Bacteriology at the University of Washington

1916
UW College of Mines and the Northwest Experiment Station

1926
Geology Giant: Richard E. Fuller

1929
Henderson and the Applied Physics Lab
Early Ethnographic Recordings in the Pacific Northwest

1930
Ethnobotany of Western Washington

1932
Super Fish--The Donaldson Trout and Salmon

1934
The Kirsten Wind Tunnel
Geology Giant: J. Hoover Mackin

1935
Howard A. Coombs: Pacific Northwest Engineering Geologist

1943
X-Ray Crystallography Helps Solve the Mystery of Protein Structure

1945
Alaska Salmon Program

1947
Breaking Trail in Bioengineering
Herschel Roman: Pioneer in Yeast Genetics

1948
Learning the Molecular Dance
Fluorine Chemistry

1950
Life's Power Switch--Protein Phosphorylation
The Finite Element Method
Harry E. Wheeler and the Development of Sequence Stratigraphy

1953
Double Whammy: Lysogenic Conversion

1955
Bone Marrow Grafting: A Story of Man and Dog
The High-Seas Salmon Program
Rescue of "Lake Stinko"

1956
Surgery Pioneers

1957
Dr. Mushroom

1960
John Bonica and the Pain Center
Ultrasound
Pioneers in Kidney Dialysis: From the Scribner Shunt and the Mini-II to the `One-Button Machine'
Never Too Thin: The Physics of Two-Dimensional Matter
Atmospheric Quirks--Oscillation of Equatorial Winds
Geographic Information Systems
Electromagnetic Research in Antarctica
Standardizing Clinical Microbiology
Hybrid Cottonwoods and Poplars: Faster than Fir

1962
Blood Coagulation

1963
The Bruce Protocol
NASA Program in Ceramic Research

1964
The Protease Chase

1965
The Washington State Input-Output Model

1966
Ion Channels

1967
How White Cells Wage War

1969
Least-Invasive Surgery
Lions' Eye Bank
Epidemiology of Hepatitis B: From Carrier to Cancer
Statistical Methods for Case-Control Studies
Sulfate Aerosol and Global Warming
The Regional Forest Nutrition Research Project
The Keystone Species Hypothesis
"A Whole lot o' Shakin' Goin' On": The Pacific Northwest Seismograph Network

1970
Medic One
Stardust

1971
WAMI: A New Concept in Medical Education
The Clinical Cyclotron
Tiny Wiggles Pack a Wallop: X-Ray Absorption Fine Structure (XAFS)

1973
Fetal Alcohol Syndrome
Getting to the Heart of Atherosclerosis
Corralling the Elusive Electron

1975
Malleable Memories
Coaching the Coaches
Economic Factors and Life Expectancy

1976
Not Just Beating Their Gums: Establishing Modern Periodontology
Martian Meteorology

1977
Knowledge Is Power
A Natural Form of Genetic Engineering
Infant Development

1978
Social Exchange Theory
Preventing Teenage Pregnancy

1979
Parent-Child Interaction
Learning to Take the Heat: Insulation for the Space Shuttle
Silicon Chips in the Pacific Northwest

1980
Rain, Hail, Sleet, or Snow? Ask Mass.
NMR Spectrometry: Powerful Probe of Molecular Structure
Safer Software
Tilings and Patterns
Cracking One of Math's Toughest Nuts
Center for Urban Horticulture
Statistical Methods in Sociology

1981
A Triumph of Biotechnology: Genetically-Engineered Hepatitis Vaccine
The Cell Cycle
Life in the Blast Zone: Recovery at Mount St. Helens
Sending Kids on a Positive Trajectory

1982
"Try to Relax"
The Transgenic Mouse

1983
The Ram Accelerator
Steady On: New Technology to Eliminate Voltage Flicker
Probing the Mysteries of Sea-Floor Volcanoes and Hydrothermal Vents
Molluscan Aquaculture and the Triploid Oyster

1985
The Seattle Foot
Blood Builders: Correcting Anemia of Kidney Failure
On the Trail of Osteoporosis

1986
Brain Mapping
The Pressure Is On: High-Pressure Mineral Physics
A Delicate Balance: High-Precision Gravity Measurements

1987
To Hear Again
Cloning the Gene for a Natural Insecticide
Ancient Quakes

1989
A New Bug That's Full of Surprises: Chlamydia pneumoniae
Drug Interactions
Columbia River Salmon Passage Model

1990
Ecogenetics
Prenylation of Proteins
Table-Top Physics
Pressure Paint Improves Airplane Design
Understanding El Niño
Reading the Climate Record in Ice: The Taylor Dome Ice Core Project, Antarctica
Of Slug Slime, Spider Silk, and Mollusk Shells
Understanding Subliminal Stimuli

1991
Softbots
Imaging the Future

1992
Diagnostic Criteria for Chronic Facial Pain
The Sound of Language

1993
Cystic Fibrosis
Sewers in Seattle
Coral Cores Yield Climate Clues

1994
Washington State Children's Dental Health Study
Needle in a Haystack: Thrombopoetin
A New Eye on the Sky
Getting an Eyeful: Retinal Display
Canopy Crane Opens New Research Horizons

1995
Deciphering the Genetic Code
Three-Dimensional Models in a Flash
New Processes for the Total Utilization of Fish
How Many Genes to Make a New Species?

1996
The Digital Anatomist

Appendix
Award Recipients

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