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Army Funding Announcement for Extramural Biomedical R&D

Posted on July 16, 2012 at 3:01pm

From: CDMRP PUBLIC AFFAIRS [mailto:CDMRP.PUBLICAFFAIRS@AMEDD.ARMY.MIL]
Sent: Thursday, July 12, 2012 5:38 AM
To: osp@u.washington.edu
Subject: BAA for Extramural Biomedical Research and Development

 

BROAD AGENCY ANNOUNCEMENT For Extramural Biomedical Research and Development

Description

USSOCOM and “SOF Unique” Requirements. The USSOCOM seeks novel biomedical solutions to preserve the high level of performance and save the lives of Special Operations Forces (SOF) in field environments. Any projects proposed must be unique to the requirements of SOF who typically conduct combat operations in austere, remote locations without timely access to medical evacuation or elevated levels of medical care. It is these far-forward and/or isolated operations that make SOF medicine unique and result in material solutions characterized by ruggedness, light weight, small volume, and low power requirements. USSOCOM is also interested in research that will lead to improved techniques and procedures that do not necessarily require new material. Information on USSOCOM is available at: (http://www.socom.mil/)

Project Constraints: There are limitations on the duration and cost of research projects that USSOCOM will fund.  Proposed projects longer than two years will not be considered.  Projects with a total cost exceeding $700,000 will not be considered. 

This BAA is intended to solicit extramural research and development ideas, and is issued under the provisions of the Competition in Contracting Act of 1984 (Public Law 98-369), as implemented in Federal Acquisition Regulation 6.102(a) (2) and 35.016. This announcement provides a general description of USSOCOM’s research areas of interest, general information, evaluation and selection criteria, and proposal/application preparation instructions.

In accordance with FAR 6.102, projects funded under this announcement must be for basic and applied research and that part of development not related to the development of a specific system or hardware procurement. Projects should be for scientific study and experimentation directed toward advancing the state-of-the-art or increasing knowledge or understanding.  Projects that are for the development of a specific system or hardware procurement will not be considered.

The USSOCOM’s supporting contracting office, the US Army Medical Research Acquisition Activity (USAMRAA), will process proposals/applications selected for funding. The Grants/Contracting Officers at USAMRAA are the only individuals authorized to commit funds and bind the Government for awards to be funded under this Announcement.

Pre-Proposals/Pre-ApplicationsOrganizations are required to submit a project pre-proposal for consideration No Later Than (NLT) August 3, 2012 using the pre-proposal template located under the “Full Application” tab of this announcement entitled “USSOCOM Biomedical Pre-proposal template.docx.”  Pre-proposals will be submitted via email to USSOCOM.biomedical@socom.mil.  Pre-proposals must define a specific project that addresses at least one of the SOF research interest areas outlined in this BAA.  In addition, it is essential that each pre-proposal describes how the project will be beneficial and unique to SOF. Brochures or other descriptions of general organizational or individual capabilities will not be accepted as a pre-proposal. The Principle Investigator (PI) will receive a decision letter or e-mail regarding the pre-proposal NLT September 1, 2012.

 Full Proposals/Applications:  Full proposals will be submitted electronically using Grants.gov no later than October 12 2012.  Note that October 12, 2012 is the last day that full proposals will be accepted, so proper planning is essential and early submissions are highly encouraged.  Receipt of full proposals will be acknowledged by e-mail or postcard.  An award decision will be rendered by the Government on or around January 1, 2013. 

Eligible Investigators:                          

All individuals, regardless of ethnicity, nationality, or citizenship status, who are employed by, or affiliated with an eligible organization, are eligible.

Investigators are cautioned that awards are made to organizations, not individuals. A principal investigator (PI) must submit a proposal/application through an eligible organization in order to receive support.

Research Areas of Interest

Damage Control Resuscitation

SOF medical personnel require capabilities for far-forward medical care to reduce the mortality and morbidity associated with major battlefield wounds and injuries.  The primary emphasis is to research, apply and/or develop medical techniques and materiel (medical devices, drugs, and biologics) for early intervention in life-threatening battle injuries when MEDEVAC is not possible.  SOF medical personnel place a premium on medical equipment that is small, lightweight, ruggedized, and designed for operation in extreme environments. The equipment must be easy to use, require minimum maintenance, and have low power consumption.  Drugs and biologics should not require refrigeration or other special handling.  All materiel and related techniques must be simple and effective Research projects may apply existing scientific and technical knowledge for which concept and/or patient care efficacy have already been demonstrated to meet SOF requirements.   The three project areas under “Damage Control Resuscitation” to which SOF will give highest consideration are:

Global Treatment Strategies.  The proposed project must research, apply and/or develop effective treatment strategies that simultaneously address all the following elements: hypotensive resuscitation, optimal fluid(s), uncomplicated shock, and traumatic brain injuries.  These strategies must be optimized for patients in far forward areas who must be treated for several hours.

Field Diagnostics.  Under this research area, there are three sub-areas: 1) effectively assessing the depth and quality of shock, 2) determining intracranial pressure, and 3) evaluating blood for type/cross matching and for the presence of pathogens.  Any research must consider the need for small, lightweight applications with low/negligible power consumption, and applicability for rapid ruggedization and fielding.

Analgesia.  The proposed project must research, apply and/or develop novel analgesia approaches that provide optimal agents and optimal delivery methods that are effective not only at the point of injury but for a prolonged period  of field care (days, not hours).

 

Environment-Specific Medicine 

SOF personnel must often operate for extended periods of time in environments that expose them to extremes in altitude, temperature, humidity, wind, etc.  In addition, the environment may be compromised due to chemical, biological, and radiological contamination.  The primary emphasis is to research, apply and develop techniques and materiel (medical devices, drugs, and biologics) to ensure sustained human performance and effectiveness while operating in harsh environmental conditions, wearing appropriate personal protective equipment.  SOF places a premium on medical equipment that is small, lightweight, ruggedized, and designed for operation in extreme environments. The equipment must be easy to use, require minimum maintenance, and have low power consumption.    Drugs and biologics should not require refrigeration or other special handling.  All materiel and techniques must be simple and effective.  Research projects may apply existing scientific and technical knowledge for which concept and/or patient care efficacy have already been demonstrated to meet SOF requirements.  The three project areas under “Environment-Specific Medicine” to which SOF will give highest consideration are:

Optimal Acclimatization Strategy.  The proposed project must research, apply and/or develop novel approaches that provide rapid and sustainable human acclimatization for extremes in temperature, altitude and time change (circadian acclimatization). 

High Altitude Pulmonary Edema/High Altitude Cerebral Edema.  The proposed project must research, apply and/or develop novel treatment approaches, either pharmaceutical interventions or alternative treatments, for high altitude pulmonary edema and /or high altitude cerebral edema.

Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) Rapid Diagnostics.  The proposed project must research and apply and/or develop novel approaches that will diagnose human exposure to chemical, biological, radiological, nuclear, and high yield explosives in near real time.

 

Force Protection

SOF personnel must be protected from extreme environments, contaminated areas, and repetitive low-impulse blast exposures.  The primary emphasis of this research is to explore alternatives and/or new approaches to presently fielded Personal Protective Equipment (PPE).  SOF medical personnel place a premium on medical equipment that is small, lightweight, ruggedized, and designed for operation in extreme environments. The equipment must be easy to use, require minimum maintenance, and have low power consumption.   Drugs and biologics should not require refrigeration or other special handling.  All materiel and techniques developed must be simple and effective. Research projects may apply existing scientific and technical knowledge for which concept and/or patient care efficacy have already been demonstrated to meet SOF requirements.   The three project areas under “Force Protection” to which SOF medical personnel will give highest consideration are:

PPE.  The proposed research must develop novel approaches for SOF personnel that provide comparable or better performance as existing PPE but with reduced mass, volume, and power consumption (if applicable). 

Preventive Medicine.  Two sub-areas of interest are: 1) rapid field diagnostics, and 2) universal anti-venin. Any research must consider the need for small, lightweight applications with low/negligible power consumption, and applicability for rapid ruggedization and fielding.  Any universal anti-venin should not require refrigeration or other special handling.

Repetitive low-impulse blast exposure.  Research that develops novel material and/or approaches to protect SOF personnel from repetitive exposures to low-impulse blasts. 

 

Canine Medicine

SOF personnel rely on the capabilities of their canines.  The primary emphasis of this research area is to explore alternatives and/or new approaches to sustain SOF canine performance in a combat.  SOF medical personnel place a premium on canine-specific approaches that are effective in extreme environments and do not require significant logistics support. The application must be easy to use, require minimum maintenance, and have low power consumption.  Drugs and biologics for canines should not require refrigeration or other special handling.  All materiel and techniques developed must be simple and effective. Any research must consider the need for small, lightweight applications with low/negligible power consumption, and applicability for rapid ruggedization and fielding. The seven project areas under “Canine Medicine” to which SOF will give highest consideration are:

Altitude Readiness.  Research to develop novel approaches/treatment for SOF canines that address either optimal acclimatization strategies or positive diagnostic tests.  Proposals may also address pharmaceutical interventions, and alternative treatments for High Altitude Pulmonary Edema/High Altitude Cerebral Edema. 

Olfaction.  Research to develop novel approaches/treatment for SOF canines that ensures optimum olfactory performance during combat operations.

Optimal Nutrition.  Research to develop optimal nutrition strategies for canines throughout the spectrum of warfare in diverse environments to ensure sustained performance.

Optimal Anesthesia Protocol.  Research to develop optimal anesthesia protocols for the routine and emergency field treatment of canines in diverse environments.

Optimal Trauma Resuscitation Strategy.  Research to develop novel approaches/treatments to support optimal trauma resuscitation strategies for canines in diverse environments.

Visual spectrum.  Research to develop novel approaches/treatment for SOF canines to ensure optimum visual performance during combat operations.

Post Trauma Training / Behavioral Issues.  Research to develop novel approaches/treatment for SOF canines to restore performance in canines that present behavior and/or post-trauma issues.

 

Agency Contact: Questions concerning the preparation of proposals can be emailed to (qa.ussocombaa@amedd.army.mil).

 

The full program announcement and application package can be found on Grants.gov, funding number W81XWH-USSOCOMBAA-12-1. 

 

http://www07.grants.gov/search/search.do;jsessionid=0LthP2QX0Dgvkh5Fp1DHKKvwrJDLf3K76dhyw1h5cy5wCK4ztDW8!1770978411?oppId=182613&mode=VIEW

 

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