Institute for Stem Cell and Regenerative Medicine
January 18, 2021
Researchers use lasers and molecular tethers to create perfectly patterned platforms for tissue engineering
Researchers at the University of Washington have developed a technique to modify naturally occurring biological polymers with protein-based biochemical messages that affect cell behavior. Their approach, published the week of Jan. 18 in the Proceedings of the National Academy of Sciences, uses a near-infrared laser to trigger chemical adhesion of protein messages to a scaffold made from biological polymers such as collagen, a connective tissue found throughout our bodies.
November 26, 2019
Six UW faculty members named AAAS fellows
The American Association for the Advancement of Science has named six faculty members from the University of Washington as AAAS Fellows, according to a Nov. 26 announcement. They are part of a cohort of 443 new fellows for 2019, all chosen by their peers for “scientifically or socially distinguished efforts to advance science or its applications.”
May 20, 2019
Scientists use molecular tethers and chemical ‘light sabers’ to construct platforms for tissue engineering
In a paper published May 20 in the journal Nature Materials, a team of researchers from the University of Washington unveiled a new strategy to keep proteins intact and functional in synthetic biomaterials for tissue engineering. Their approach modifies proteins at a specific point so that they can be chemically tethered to the scaffold using light. Since the tether can also be cut by laser light, this method can create evolving patterns of signal proteins throughout a biomaterial scaffold to grow tissues made up of different types of cells.
January 16, 2018
Researchers program biomaterials with ‘logic gates’ that release therapeutics in response to environmental triggers
Drug treatments can save lives, but sometimes they also carry unintended costs. After all, the same therapeutics that target pathogens and tumors can also harm healthy cells. To reduce this collateral damage, scientists have long sought specificity in drug delivery systems: A package that can encase a therapeutic and will not disgorge its toxic cargo…
August 1, 2013
Burnt sugar-derivative reduces muscle wasting in fly and mouse models of muscular dystrophy
A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in insect and animal models of Duchenne muscular dystrophy.
