UW Today

FDA-approved immune-modulating drug unexpectedly benefits mice with fatal mitochondrial defect

Rapamycin, an anti-rejection drug for organ transplant patients, has now been shown to increases survival in and delayed symptoms of Leigh’s syndrome. The drug appears to cause a metabolic switch that bypasses the mitochondrial deficiency.

Gene for most common childhood cancer identified

In children with this form of leukemia, damage to chromosome 9 removes part of a normal copy of the gene in question, and leaves the mutated copy unopposed.

Burnt sugar-derivative reduces muscle wasting in fly and mouse models of muscular dystrophy

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in insect and animal models of Duchenne muscular dystrophy.