Research Activities

Our research programs center on the diagnosis, treatment, and quality of life of children and adolescents with gastrointestinal and liver diseases. Current topics of focus include therapy trials for viral hepatitis, acute liver failure, nonalcoholic fatty liver disease, and inflammatory bowel disease. We also have ongoing research in the area of liver transplantation and immune activity in maternal micochimerism in inflammatory bowel disease and biliary atresia. Many of these studies are being performed in collaboration with other centers around the United States.

  • Pathogenesis, progression, and treatment of pediatric genetic cholestatic liver diseases including biliary atresia, progressive familial intrahepatic cholestasis, alpha-1-anti trypsin deficiency, and bile acid deficiency/li>
  • Epidemiology, pathogenesis, and treatment of chronic viral hepatitis B and C/li>
  • Pathogenesis and treatment of non-alcoholic steatohepatitis/li>
  • Pathogenesis and treatment of intestinal failure/li>
  • Outcome disparities in liver transplantation/li>
  • Indicators of medical frailty among patients listed for liver transplant/li>
  • Hepatocellular mechanisms and molecular toxicology behind the hepatotoxicity of many widely-used medicinal herbs

For more information on this specialty, please visit the Gastroenterology webpage.