University of Washington School of Medicine
Seattle Children's
Department of Pediatrics Newsletter

DATE : 2008-12-05

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Items to be covered in this edition:

  1. Important Dates
  2. Faculty News
  3. Faculty Publications and Presentations

Message from the Chair

As all of us are aware, financial reserves and availability to cash are currently challenged. This is true for the University of Washington and Seattle Children’s despite their strong financial position. Our Department is not immune to these economic forces. We are asking our leaders and you, the faculty, to be thoughtful in your travel, discretionary expenses, and recruiting costs. You will soon receive cost containment policies from Seattle Children’s, and possibly the UW. One policy to take effect quickly will eliminate catering for day time events and meetings. We ask that our Divisions respect this new policy and that you understand the exigencies requiring economic “belt tightening”. Thank you for your support and commitment to our missions.

Bruder Stapleton, MD

top I. IMPORTANT DATES

December 11, 2008: "The World Report on Child Injury Prevention": An International Forum on Children’s Health, 2:00-5:00pm in Hogness Auditorium, University of Washington. An international forum on children’s health, featuring the US introduction of the World Health Organization and UNICEF-sponsored World Report on Child Injury Prevention. The event will provide an overview of children’s injuries worldwide and generate discussion of prevention strategies. Featured speakers include international injury experts and representatives from WHO and UNICEF. The event is complimentary and open to individuals with an interest in global children’s health. Email hiprc2@u.washington.edu to register.

December 18, 2008: Grand Rounds: The Department of Pediatrics: Educating the Next Generation of Pediatric Leadership. Bruder Stapleton, MD; Chief Academic Officer, Professor and Chair, Department of Pediatrics.

January 21, 2009: Promotion preparation meeting. 7:30-8:30am, Wright Auditorium at Children's. The Department of Pediatrics Promotions Committee requires that faculty members who will be considered in the summer/fall of 2009 for promotion to Associate Professor or Professor attend one of these seminars. If you are being considered in 2009 for promotion (to be effective July 1, 2010), you, your Division Head, and your Division Head's assistant MUST attend one of these meetings even if you attended last year (note, you do not all need to attend on the same date). For more information or to RSVP your attendance at one of these meetings, contact Diane Wade (206-987-1713 or dmw@u.washington.edu).

February 17, 2009 (NOTE- DATE CHANGED FROM FEB 24): Promotion preparation meeting. 5-6pm, G1026 at Children's. The Department of Pediatrics Promotions Committee requires that faculty members who will be considered in the summer/fall of 2009 for promotion to Associate Professor or Professor attend one of these seminars. If you are being considered in 2009 for promotion (to be effective July 1, 2010), you, your Division Head, and your Division Head's assistant MUST attend one of these meetings even if you attended last year (note, you do not all need to attend on the same date). For more information or to RSVP your attendance at one of these meetings, contact Diane Wade (206-987-1713 or dmw@u.washington.edu).

February 26, 2009: SAVE THE DATE- Next faculty meeting. More information forthcoming. Childcare will be available from 5-8:30 PM. Please contact Diane Wade (dmw@u.washington.edu) for more information.

April 24, 2009: SAVE THE DATE- Fellows Research Day, Bldg 1, SCRI. More information and call for abstracts forthcoming.

top II. FACULTY NEWS

Bruder Stapleton, MD has been named co-Editor-in-Chief for UpToDate in Pediatrics. Sheldon L. Kaplan, MD and Bruder Stapleton, MD are taking over for Ralph D. Feigin, MD who passed away in August.

John K. McGuire, MD has been elected into the membership of the Society for Pediatric Research.

top III. FACULTY PUBLICATIONS, INVITED LECTURES, PRESENTATIONS

Joseph T. Flynn, MD, MS, Professor of Pediatrics, Division of Nephrology: Hypertension in the young: epidemiology, sequelae and therapy. Nephrology Dialysis Transplantation 2008; doi: 10.1093/ndt/gfn597

Cate Pihoker, MD: The delivery of ambulatory diabetes care: structures, processes, and outcomes of ambulatory diabetes care. Pihoker C, Forsander G, Wolfsdorf J, Klingensmith GJ. Pediatric Diabetes 2008: 9: 609–620. (Guidelines for the International Society for Pediatric and Adolescent Diabetes)

Rebecca Partridge, MD, Assistant Professor of Pediatrics: Acute Asthma In The Pediatric Emergency Department. Pediatric Emergency Medicine Practice, Nov 2008.

Kenneth A. Schenkman, M.D., Ph.D, Pediatric Critical Care Medicine, Associate Professor, Pediatrics presented “Noninvasive Oxygen Monitoring for Shock” at the UW Foster School of Business Science and Technology Showcase, put on by the Center for Innovation and Entrepreneurship (CIE) and the Science & Engineering Business Association (SEBA) and was awarded the “ARCH 1st Runner-up prize.” This event was a showcase of emerging technology developed at the UW, and the presentations were judged by a panel of members from the venture capital investment community. Dr. Schenkman has also recently completed 10 years of service at Seattle Children’s Hospital. Congratulations, Ken.

Anne Stevens, MD:

  1. Chimeric Maternal Cells with Tissue-Specific Antigen Expression and Morphology are Common in Normal Infant Tissues. Stevens AM, Hermes HM, Kiefer MM, Rutledge JC, Nelson JL (2008) Pediatric and Developmental Pathology. Oct 21:1. [Epub ahead of print]
  2. Continued disease activity in a patient with multiple sclerosis after allogeneic hematopoietic cell transplantation. Lu J-Q, Storek J, Metz L, Yong VW, Stevens AM, Nash R, Joseph JT (2008) Arch Neurol. In Press.
  3. Are pediatric autoimmune diseases primarily genetic diseases? Shaw E, Stevens AM (2008) Current Opinion in Rheumatology 20(5) 589-94.

Ken Feldman, MD:

  1. Feldman KW. Contributor & Peer Reviewer. For: The Visual diagnosis of child abuse on CD-ROM. 3rd Ed. Lowen D and Reece RM, Eds. AAP, 2008.
  2. Feldman KW. Immersion injury in child abuse and neglect. For: Child Abuse: Medical diagnosis and management. 3rd Ed. Reece RM & Christian CW, Eds. AAP, 2008:601-616.

Hans Ochs, MD, and Troy Torgerson, MD, PhD:

  1. Primary immune deficiency disorders presenting as autoimmune diseases: IPEX and APECED. Moraes-Vasconcelos D, Costa-Carvalho BT, Torgerson TR, Ochs HD.J Clin Immunol 2008;28 Suppl 1:S11 S19.
  2. Familial hemophagocytic lymphohistiocytosis in two brothers with X-linked agammaglobulinemia. Schultz KA, Neglia JP, Smith AR, Ochs HD, Torgerson TR, Kumar A.Pediatr Blood Cancer 2008;51(2):293-295.
  3. Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome. Renner ED, Rylaarsdam S, Anover-Sombke S, Rack AL, Reichenbach J, Carey JC, Zhu Q, Jansson AF, Barboza J, Schimke LF, Leppert MF, Getz MM, Seger RA, Hill HR, Belohradsky BH, Torgerson TR, Ochs HD. J Allergy Clin Immunol 2008;122(1):181-187. PMID: 18602572

Hans Ochs, MD, David Rawlings, MD, Carol Miao, PhD: Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice. Peng B, Ye P, Blazar BR, Freeman GJ, Rawlings DJ, Ochs HD, Miao CH. Blood 2008;112(5):1662-1672.PMCID: PMC2518877 (Available on 09/01/09)

Hans Ochs, MD:

  1. Restricted immunoglobulin constant heavy G chain genes in primary immunodeficiencies. Oxelius VA, Ochs HD, Hammarstrom L. Clin Immunol 2008;128(2):190-198. PMID: 18502179
  2. WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function. Westerberg LS, de la Fuente MA, Wermeling F, Ochs HD, Karlsson MC, Snapper SB, Notarangelo LD. Blood 2008;112(10):4139-4147. PMCID: PMC2581999
  3. Patients with abnormal IgM levels: Assessment, clinical interpretation and treatment. Ochs HD. Ann Allergy Asthma Immunol 2008; 100 (5):509-511. PMID: 18517086
  4. Effect of Therapeutic Integrin (CD11a) Blockade with Efalizumab on Immune Responses to Model Antigens in Humans: Results of a Randomized, Single Blind Study. Krueger JG, Ochs HD, Patel P, Gilkerson E, Guttman-Yassky E, Dummer W. J Invest Dermatol 2008.
*Please let us know of your latest publications, awards, and honors by emailing Brooke Freed.