Children's Hospital and Regional Medical Center
Department of Pediatrics Newsletter
DATE : 2007-06-29
ITEMS TO BE COVERED IN THIS NEWSLETTER:
Important Dates
Faculty/Resident Recognitions
Beth Ebel named director of Harborview Injury Prevention Research Center
Faculty News
Faculty Publications and Presentations
Friday and Saturday, July 13-14: The third annual Pediatric Bioethics Conference “Current Controversies: Navigating Conflicts When Parents and Providers Disagree about Medical Care”. Bell Harbor International Conference Center, Seattle, Washington. For questions or more information about the conference, please contact Angel Latterell, conference project manager, at (206) 987-7825 or angel.latterell@seattlechildrens.org.
Tuesday, July 24: Department of Pediatrics Faculty Picnic at Gasworks Park. RSVP to Diane Wade (dmw@u.washington.edu)
DEADLINE - Tuesday, July 31: Application for American Pediatric Society Due. www.aps-spr.org
August 16-19, 2007: The North Pacific Pediatric Society (NPPS) will have its 175th Conference this coming August 16-19, 2007, at the Harrison Hot Springs Resort & Spa, in Harrison Hot Springs, British Columbia Canada. The program can be accessed on the Society's web site at: www.northpacificpediatricsociety.org
Monday, September 24, by 5:00 PM: The Autumn 2007 round of the Royalty Research Fund (RRF) Proposals are due Monday, September 24, by 5:00 PM. The application, packet, and information about previous awards may be found on the Office of Research website at: http://www.washington.edu/research/rrf.html. Contact the RRF program staff, Barbara Thompson (bthompso@u.washington.edu), and Peter Wilsnack (doogieh@u.washington.edu), if you have questions about the program.
September 28-29, 2007: Centennial celebration- Medical Symposium and Alumni reunion Sept 28-29 Children’s Hospital and Grand Hyatt Seattle.
The following individuals have been recognized by their colleagues and students. Please join me in congratulating them on their contributions to the Department, Children's Hospital, the University of Washington, their colleagues and most of all to the patients who are the final beneficiaries of their service.
Faculty Mentor Award (A new award and first presentation): Russ Geyer, MD
Faculty Teaching Awards: Denise Sushan, MD, and David Loren, MD
Stanley Stamm Role Model Award: Linda Quan, MD
Resident Award Winners included:
Abraham Bergman Harborview Medical Center Award: Eva Moore, MD
Family Centered Care Awards (Named by parents): Amy Carter, MD and Melissa Walsh, MD
Student Teaching Award (voted by medical students): Kelly Evans, MD
Fellow Teaching Award (voted by residents): Amanda Bunn, MD
BETH EBEL NAMED DIRECTOR OF HARBORVIEW INJURY PREVENTION RESEARCH CENTER
Beth Ebel, UW assistant professor of pediatrics, has been named director of the Harborview Injury Prevention and Research Center (HIPRC). Ebel began leading the center on June 1.
The HIPRC is one of 10 injury-control centers established by the U.S. Centers for Disease Control and Prevention. The center's 40 staff are devoted to research, education, and prevention programs aimed at reducing the impact of trauma and improving injury prevention and trauma treatment programs.
Ebel studies injury prevention and health behaviors, and has led research on the Seattle campaign encouraging children's car booster seats. She also led a project examining the effectiveness of booster seats in protecting children in car crashes.
Luke Hoffman, MD, PhD has been selected to receive a 2007 ICAAC Young Investigator Award. On behalf of the Officers of the American Society for Microbiology (ASM), the Committee on Awards of the American Academy of Microbiology, and the ICAAC Young Investigator Award Selection Committee.
Dr. Dimitri Christakis has been invited to serve as a member of the Health Services Organization and Delivery Study Section, Center for Scientific Review from July 1, 2007-June 30, 2011.
Shilpi Chabra, MD, was awarded intramural funding from the UW Neonatal Bioresearch Fund for her project "Prevalence of gastroschisis in Washington State and identification of associated risk factors"
David Loren, MD, was accepted into the UW School of Medicine College Faculty program.
Thomas Strandjord, MD, was awarded an AAP Neonatal Resuscitation Program Research Grant & Young Investigator Award "Screen-based computer simulation as an adjunct to conventional NRP training" for $10,000 7/2007-6/2008.
Peter Tarczy-Hornoch, MD, is the recipient of the 2007 Excellence in Teaching Award in Biomedical and Health Informatics, University of Washington.
Peter Tarczy-Hornoch, MD, serves on the Steering Committee of the American Medical Informatics Association (AMIA) Academic Forum whose mission is to promote the development of biomedical and health informatics as an academic discipline. The inaugural annual AMIA Academic Forum meeting which Peter has been helping plan is being held at Stanford this year. One of the keynote speakers is Bruder Stapleton, MD who will be on a panel titled "Fostering an Academic Discipline - Lessons from Other Fields".
Dan Doherty, MD, PhD, and Ian Glass, MD have been funded $37,500 by the Royalty Research grant for one year. The project is entitled: Identifying Joubert syndrome genes by SNP genotyping combined with global expression profiling.
New College faculty from the Department of Pediatrics: Ted Carter, MD will be starting as a College faculty member on July 1, 2008. David Loren, MD has been selected for a College position beginning July 2009.
Puget Sound Partners for Global Health's Scientific Review Committee recently approved Dr. Allison Eddy’s pilot project, Impact of Kidney Dysfunction on Mortality Rates in Ugandan Children Hospitalized with Acute Infections, for funding in the amount of $75,000.
Janet Englund, MD has been accepted as a member on the ACIP (Advisory Committee on Immunization Practices) starting July 1, 2007, and will be chairman of the HPV vaccine committee.
Rob Mazor, MD has been selected as site co-PI for the Berlin Heart EXCOR® Pediatric VAD Trial.
Dr. Jackie Starr’s R01 on Craniofacial Microsomia was funded: R01 DE 017421 (Starr, PI) NIH NIDCR. "Craniofacial Microsomia and Genetic Variation in Hemostasis and Vasculogenesis" will address the vascular disruption hypothesis by conducting a case-parent triad/case-control study and will evaluate associations between craniofacial microsomia occurrence and common genetic variants in three pathways involving retinoic acid, endothelin, and thrombin activities.
The CHRMC International Outreach Program will include the Craniofacial Center in its first year of funding. The SmileTrain has agreed to help with the costs.
FACULTY PUBLICATIONS AND PRESENTATIONS
Rob Mazor, MD and Harris Baden, MD: "Current Trends in Pediatric Organ Donation Following Cardiac Death" has been accepted for publication in Pediatrics.
Drs. Russ Migita and Ken Feldman authored the following chapter: Migita, R & Feldman, K. Visceral injury in Child Abuse. Meadow, R, Mok, J and Rosenberg, D, eds. ABC of Child Protection-4th Ed. Blackwell Publishing, BMJ Books. Oxford, UK. 2007;30-34.
Dimitri Christakis, MD, MPH: Television and DVD/Video Viewing in Children Younger than 2 years. Arch Peds, May 2007.
Bruder Stapleton, MD: What is a pediatrician and who is asking? Editorial. J Pediatr 2007; 150:577-8
Drs. Christine Gleason, Marcella Mascher-Denen, and Sandra Juul: McPherson RJ, Gleason C, Mascher-Denen M, Chan M, Kellert B, Juul SE. A new model of neonatal stress which produces lasting neurobehavioral effects in adult rats. Neonatology 2007; 92: 33-41
Drs. Eric Demers and Sandra Juul: McPherson RJ, Demers EJ, Juul SE. Safety of high-dose recombinant erythropoietin in a neonatal rat model. Neonatology 2007; 91: 36-43.
Drs. Pamela Statler and Sandra Juul: Statler PA, McPherson RJ, Bauer LA, Kellert BA, Juul SE. Pharmacokinetics of high-dose recombinant erythropoietin in plasma and brain of neonatal rats. Pediatr Res 2007 Apr 5 [Epub ahead of print].
Dr. Carmen Herrera: Herrera C, Holberton J, Davis P. Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants. Cochrane Database of Systematic Reviews 2007, Issue 2, Art. No.: CD003480. DOI:10.1002/14651858. CD003480.pub3.
Drs. Dennis Mayock and Christine Gleason:
Mayock DE, Ness D, Mondares RL, Gleason CA. Binge alcohol exposure in the second trimester attenuates fetal cerebral blood flow response to hypoxia. J Appl Physiol 2007; 102: 972-977.
Mayock DE, Bennett R, Robinson RD, Gleason CA. Dopamine does not limit fetal cerebrovascular responses to hypoxia. J Appl Physiol 2007; 102: 130-134.
Dr. Richard Wennberg:
1. Invited Speaker: Pathogenesis and clinical presentation of bilirubin induced neurological dysfunction (BIND). Session II: Neonatal Hyperbilirubinemia: Biological Aspects. Neonatal Hyperbilirubinemia in Egypt: Shedding Light on Improving Outcomes, Cairo, Egypt, March 12, 2007. Organized by National Research Center Egypt, NICHD, and Fogarty International Center. Funded by US-Egypt Joint Science and Technology Fund and NIH.
2. Invited Speaker: Exchange transfusion. Session V: Management of Hyperbilirubinemia. Neonatal Hyperbilirubinemia in Egypt: Shedding Light on Improving Outcomes, Cairo, Egypt, March 13, 2007. Organized by National Research Center Egypt, NICHD, and Fogarty International Center. Funded by US-Egypt Joint Science and Technology Fund and NIH.
David Woodrum: Panel Discussant: A conversation about the Seattle Children's case [Ashley X]. The Ethical and Policy Implications of Limiting Growth in Children with Severe Disabilities, UW Disabilities Studies Program Symposium, Treuman Katz Center for Pediatric Bioethics. University of Washington School of Law, May 16, 2007
Drs. Lakshmi Rajagopal and Craig Rubens:
1. Rantanen MK, Lehtio L, Rajagopal L, Rubens CE, and Goldman A. 2007. Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion. FEBS J, 274:3128-3137.
2. Rantanen MK, Lehtio L, Rajagopal L, Rubens CE, and Goldman A. 2007. Structure of the Streptococcus agalactiae family II inorganic pyrophosphatase at 2.80 Å resolution. Acta Cryst, D63:738-743.
Dr. Andy Scharenberg:
1. Volna P., Jarjour J., Baxter S., Roffler S.R., Monnat R.J., Stoddard B.L., Scharenberg A.M. Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases. Nucleic Acids Research, 2007, 35(8):2748-2758.
2. Liu P, Scharenberg AM, Cantrell DA, Matthews SA., Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells., FEBS Lett. 2007, 581(7):1377-1382.
Drs. Hans Ochs and Troy Torgerson:
1. Heltzer ML, Choi JK, Ochs HD, Sullivan KE, Torgerson TR, Ernst LM. A Potential Screening Tool for IPEX Syndrome. Pediatr Dev Pathol, 10:98-105, 2007.
2. Torgerson TR, Linane A, Moes N, Anover S, Mateo V, Rieux-Laucat F, Hermine O, Vijay S, Gambineri E, Fischer A, Ochs HD, Goulet O, Ruemmele Frank . Severe Food Allergy as a Variant of IPEX Syndrome Caused by a Deletion in a Noncoding Region of the FOXP3 Gene. Gastroenterology, 132(5):1705-1717, 2007.
Dr. Jane Burns:
Cheung KJ Jr, Li G, Urban TA, Goldberg JB, Griffith A, Lu F, Burns JL. Pilus-mediated epithelial cell death in response to infection with Burkholderia cenocepacia. Microbes Infect. 2007 Mar 12
Gibson RL, Emerson J, Mayer-Hamblett N, Burns JL, McNamara S, Accurso FJ, Konstan MW, Chatfield BA, Retsch-Bogart G, Waltz DA, Acton J, Zeitlin P, Hiatt P, Moss R, Williams J, Ramsey BW; for the Inhaled Tobramycin in Young Children Study Group and the Cystic Fibrosis Foundation Therapeutics Development Network. Duration of treatment effect after tobramycin solution for inhalation in young children with cystic fibrosis. Pediatr Pulmonol. 2007 May 29;42(7):610-623 D'Argenio DA, Wu M, Hoffman LR, Kulasekara HD, Deziel E, Smith EE, Nguyen H, Ernst RK, Larson Freeman TJ, Spencer DH, Brittnacher M, Hayden HS, Selgrade S, Klausen M, Goodlett DR, Burns JL, Ramsey BW, Miller SI. Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients.
Mol Microbiol. 2007 Apr;64(2):512-33.
Nguyen D, Emond MJ, Mayer-Hamblett N, Saiman L, Marshall BC, Burns JL. Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypes. Pediatr Pulmonol. 2007 Jun;42(6):533-41.
*Please let us know of your latest publications, awards, and honors by emailing Brooke Freed (brooke.freed@seattlechildrens.org).