A New SAGE class is available beginning May 2007: Do’s and Don’ts of Attaching Documents to eGC1s in SAGE. This 2 hour hands-on workshop will provide practice in attaching documents (file upload) to eGC1s in SAGE. It will also address the questions that arise around the types of files that can be uploaded into SAGE, and what their corresponding file types should be. Contact Toyin Akisanya ORIStraining@u.washington.edu or (206) 616- 9096 to register or arrange to have the class delivered onsite at your location.

Monday, May 7, 6:45-8:30 PM: UW Department of Pediatrics/CHRMC Faculty and Alumni Reception at PAS. Toronto, Fairmont Royal York, Room: Tudor 8. Invite your colleagues and friends and plan to join us! No RSVP necessary.

Monday, June 4: NEXT FACULTY MEETING. 5:30-6:00PM buffet dinner; 6:00-8:00PM, Program. Sound Cafe, CHRMC. Topics to be covered: Research planning, Educational innovations, Transplantation programs.

SAVE THE DATE: Tuesday, July 24: Department of Pediatrics Faculty Picnic at Gasworks Park.

August 16-19, 2007: The North Pacific Pediatric Society (NPPS) will have its 175th Conference this coming August 16-19, 2007, at the Harrison Hot Springs Resort & Spa, in Harrison Hot Springs, British Columbia Canada. The program can be accessed on the Society's web site at www.northpacificpediatricsociety.org

FACULTY NEWS

Ted Carter, MD was named ARTist of the Month in March at Children's Hospital and Regional Medical Center for his professionalism and patient-centered care.

Craig E. Rubens, MD, PhD, received renewal of the NIH supported training grant for Pediatric Infectious Disease through April, 2012. This program seeks to train pediatricians in contemporary molecular biology so they will be equipped to answer questions relevant to infectious disease in infants and children.

Audrey R. Odom, MD, PhD, a second-year fellow in Infectious Diseases, was awarded a Pediatric Infectious Diseases Society Fellowship Award for $90,000 over two years. Dr. Odom's research focuses on the steroid biosynthesis pathway of the malaria parasite Plasmodium falciparum, as a potential target for new antimalarial drugs

FACULTY PUBLICATIONS AND PRESENTATIONS

Marissa Braff, Amanda Jones and Craig Rubens: Braff MH, Jones AL, Skerrett SJ and Rubens CE. Staphylococcus aureus Exploits Cathelicidin Antimicrobial Peptides Produced during Early Pneumonia to Promote Staphylokinase-Dependent Fibrinolysis. J Infect Dis 2007;195:1365-72.

Sunny Juul, MD: A Comparison of High-Dose Recombinant Erythropoietetin Treatment Regimens in Brain-Injured Neonatal Rats. B Kellert, R McPherson, S Juul. Pediatric Research V 61, No 4, 2007.

Eric Chow, MD, MPH, and Debra Friedman, MD, MS: Decreased Adult Height in Survivors of Childhood ALL: A report from the Childhood Cancer Survivor Study. Chow, Friedman, et al. Journal of Pediatrics April 2007.

Sing Sing Way, PhD:

1. Way, S.S., Kolumam, G.A., Havenar-Daughton, C., Murali-Krishna, K., (2007) IL-12 and type I-IFN synergize for IFN-g production by CD4 T cells, while neither are required for IFN-? production by CD8 T cells after Listeria monocytogenes infection. J Immunol 178: 4498-4505.

2. Kollmann, T.R, Reikie B., Blimkie D, Way, S.S., Hajjar, A.M., Arispe, K., Wilson, C.B. (2007) Induction of Protective immunity to Listeria monocytogenes in neonates. (J Immunol 178: 3695-3701.

3. Orr, M.T., Orgun, N.N., Wilson, C.B., Way, S.S. (2007) Cutting Edge: Recombinant Listeria monocytogenes expressing a single immune-dominant peptide confers protective immunity to herpes simplex virus-1 infection. J Immunol 178: 4731-4735.

4. Way, S.S., Sidbury, R., Crane H. (2007) Chromobacterium violaceum causing sepsis and focal ulceration in a healthy child. (Infectious Disease Clinical Practice, in press).

Hans Ochs, MD:

1. Ochs HD, Gupta D, Kiessling P, Nicolay U, Math D, Berger M, and the Subcutaneous IgG study Group. Safety and efficacy of self administered subcutaneous immunoglobulin in patients with primary immunodeficiency diseases. J Clin Immunol 26:265-273, 2006.

2. Trakultivakorn M, Ochs HD. X-Linked Agammaglobulenemia in Northern Thailand. Asian Pac J of Allergy and Immunol 24:57-63, 2006.

3. Winkelstein JA, Marino MC, Lederman HM, Jones SM, Sullivan K, Burks AW, Conley ME, Cunningham-Rundles C, Ochs HD. X-linked agammaglobulinemia: report on a United States registry of 201 patients. Medicine (Baltimore) 85(4): 193-202, 2006.

4. Minegishi Y, Saito M, Morio T, Watanabe K, Agematsu K, Tsuchiya S, Takada H, Hara T, Kawamura N, Ariga T, Kaneko H, Kondo N, Tsuge I, Yachie A, Sakiyama Y, Iwata T, Bessho F, Ohishi T, Joh K, Imai K, Kogawa K, Shinohara M, Fujieda M, Wakiguchi H, Pasic S, Abinun M, Ochs HD, Renner ED, Jansson A, Belohradsky BH, Metin A, Shimizu N, Mizutani S, Miyawaki T, Nonoyama S, Karasuyama H. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity, 25(5): 745-55, 2006.

5. Smith CIE, Ochs HD, Puck JM. Genetically Determined Immunodeficiency Diseases: A Perspective. In: Ochs HD, Smith CIE Puck JM. (Eds.), Primary Immunodeficiency Diseases, A Molecular and Genetic Approach (2nd ed.) New York: Oxford University Press, pp. 3-15, 2007.

6. Ochs HD, Rosen FS. Wiskott-Aldrich Syndrome. In: Ochs HD, Smith CIE, Puck JM. (Eds.), Primary Immunodeficiency Diseases, A Molecular and Genetic Approach (2nd ed.) New York: Oxford University Press, pp. 454-469, 2007.

7. Tsuboi S, Nonoyama S, Ochs HD: Wiskott-Aldrich syndrome protein is involved in αIIbβ3-mediated cell adhesion. EMBO reports 7(5): 506-511, 2006.

8. Ochs HD, Thrasher AJ. The Wiskott-Aldrich syndrome. J Allergy and Clin Immunol 117:725-738, 2006.

Troy Torgerson, MD, PhD:

1. Gavin MA, Torgerson TR, Houston E, deRoos P, Ho WY, Greenberg PD, Ochs HD, Rudensky AY. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 103(17):6659-6664, 2006.

2. Torgerson, TR, Gambineri E, Ziegler ST, Ochs HD. Immune Dysregulation, Polyendocrinopathy, Enteropathy, and X-Linked Inheritance. In: Ochs HD, Smith CIE, Puck JM. (Eds.), Primary Immunodeficiency Diseases, A Molecular and Genetic Approach (2nd ed.) New York: Oxford University Press, pp. 355-366, 2007.

3. Lopes JE, Torgerson TR, Schubert LA, Anover SD, Ocheltree EL, Ochs HD, Ziegler SF. Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor. J Immunol 177(5): 3133-3142, 2006.

*Please let us know of your latest publications, awards, and honors by emailing Brooke Freed (brooke.freed@seattlechildrens.org).